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Psychosocial Genomics: A Bridge from Mind to Gene

Presented by Richard Hill MA. Psychosocial Genomics: A Bridge from Mind to Gene. Australia. Psychosocial Genomics. The deep psychobiological process of “activity or experience-dependent gene expression and brain plasticity” associated with creativity and psychotherapy. Becoming

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Psychosocial Genomics: A Bridge from Mind to Gene

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  1. Presented by Richard Hill MA Psychosocial Genomics: A Bridge from Mind to Gene Australia

  2. Psychosocial Genomics The deep psychobiological process of “activity or experience-dependent gene expression and brain plasticity” associated with creativity and psychotherapy.

  3. Becoming Human

  4. Therapeutic Brain Plasticity

  5. Gene expressionEpigenetic Silencing • State dependent gene expression • Activity dependent gene expression • Epigenetic marking – methylation, acetylation. Access of transcription factors to promoter region. • Nucleosome tension – ionic tightness.

  6. Rossi Stage One: Initiation & Creative Expectation Stage Two: Incubation, Access Current Experience BREAKOUT Stage Three: Illumination, Aha! Constructing Future Mind Stage Four: Evaluation, Planning, & Reality Testing

  7. Ultradian Rhythms

  8. Meaning Making Meaning responsive

  9. Gene Expression Studies BDNF Endogenous BDNF regulates induction of intrinsic neuronal growth programs in injured sensory neurons Geremia1, Lina, Pettersson, Hasmatali, Hryciw1, Danielsen, Schreyer1 & Verge Experimental Neurology July 29, 2009 Article in Press Post 911 Gene Expression Patterns Associated with Posttraumatic Stress Disorder Following Exposure to the World Trade Center Attacks Yehuda, Cai, Golier, Sarapas, Galea, Ising, Rein, Schmeidler, Müller-Myhsok, Holsboer & Buxbaum Biological Psychiatry 2009 April 24 Article in Press Zif268 Ribeiro, Mello, Vehlo, Gardner, Jarvis, & Pavlides, (2002) Induction of hippocampal long-term potentiation during waking leads to increased extra hippocampal zif-268 expression during ensuing rapid-eye-movement sleep. Journal of Neuroscience, 22 (24): 10914-10923.

  10. Gene Expression Studies Tickling rat Positive emotion-specific changes in the gene expression profile of tickled rats Hoi, Hayashi, Nakagawa, Sakamoto, Urayama & Murakami Molecular Medicine Reports 2: 157-161, 2009 Music Appreciation and Attachment Musical Aptitude Is Associated with AVPR1A-Haplotypes Ukkola , Onkamo , Raijas , Karma , Jarvela (2009 PLoS ONE 4(5): e5534. doi:10.1371/journal.pone.0005534 • Hypnosis A Pilot Study of Positive Expectations and Focused Attention via a New Protocol for Optimizing Therapeutic Hypnosis and Psychotherapy Assessed with DNA Microarrays: The Creative Psychosocial Genomic Healing Experience  Rossi,Iannotti, Cozzolino, Castiglione, Cicatelli, Rossi The International Journal of Sleep, Dreams and Hypnosis Vol 10, No.2, 2008

  11. The Purpose of Life

  12. The Purpose of Life To creatively participate in the experience

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