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J. Stephen Huff, MD Associate Professor Department of Emergency Medicine University of Virginia Charlottesville, Virginia. EMS Triage and the ED Transfer of Ischemic Stroke Patients. Disclosures. ACEP Clinical Policies Committee FERNE support by Abbott, Eisai, Pfizer, UCB, Concentric Medical.
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J. Stephen Huff, MDAssociate ProfessorDepartment of Emergency MedicineUniversity of VirginiaCharlottesville, Virginia
Disclosures • ACEP Clinical Policies Committee • FERNE support by Abbott, Eisai, Pfizer, UCB, Concentric Medical
Questions / Answers? • Who should be transferred to a another hospital for specialized stroke care? When? • OR • EMS direct transport to center?
Questions / Answers? • Which patient? • What time? • What hospital? • What technologies?
Current systems • Few direct EMS to stroke centers • Fragmented care at multiple levels • Physician attitudes and abilities vary • neurology, radiology, emergency • Hospitals variable in support • emergency, radiology, units, floors
Patients vary • Stroke mimics • Stroke syndromes • Strokes-ischemic • Strokes-intracerebral hemorrhage • Patient age, co-morbidities
Progress has been made • EMS Dispatch • priority • 911e systems • EMS training • ACLS • Others
Prehospital identification • Cincinnati Stroke Scale • LA Prehospital Stroke Screen • Time of onset • Other history • Medications
Chain-of-survival • Parallels with cardiac care striking • Goals similar • appropriate therapy to right patients • time limitations • Problems similar • Pre-planned action paths are key
Differences cardiac care • Lack of clear markers • EKG • Serum markers • Infinitely variable presentations • Different pathophysiology looks similar • Ischemic stroke • Intracerebral hemorrhage
ED and Hospital Capacity • Real issues with ED capacities • Other real demands on time • trauma emergencies • cardiac emergencies • surgical emergencies
What we know • Intravenous tPA works in select patients • -small vessel occlusions • Transcranial Doppler may aid lysis • Few patients tPA candidates • Others - interventional radiology
What we don’t know • Interventional radiology • how many patients? • which ones? • what techniques?
A brief history of IA… • Arteries could be opened… • How long to open? • Would they stay open? • Were outcomes improved?
Why might IR work? • “Clot Burden” • too much for IV thrombolytics • amount of clot • location of clot • Directed intra-arterial lytics • Directed mechanical clot extraction
Modern IR • Better neuroimaging • Better thrombolytics • Better mechanical devices
Modern IR • Impressive results at some centers in some patients…. • How to select patients?
Interventional Radiology • Select patients - large vessel occlusion • intra-arterial lytics • clot retrieval • Selected syndromes - Basilar occlusion • IV lytic failure? How to predict / monitor?
Is all IR alike? • Real world problems • Consultants • Tiers of access
Is all IR alike? • Parallels to cardiac care • At this time rapid response lacking in most centers…. • Can results be generalized?
Scenarios • Bypass all but centers with IR • OR • “Hub and spoke” with accepted evaluation protocols and performance standards • OR • Pre-defined access paths with buy-in by stakeholders
Solution-proposal • Networks • Pre-defined buy-in by institutions and groups • Rapid, appropriate transfer of rapidly but carefully selected patients • Neuroimaging prior to transfer?
GOAL - MATCH • Appropriate patients • Appropriate technology • Appropriate facility • Appropriate care providers
What might work (IMHO) • Rapid CT / CT-A at first stop • Prompt interpretation - tele? • Transfer lots of electrons, not necessarily lots of patients • Identify the anatomy • Transfer emergently 10-15% • Delayed transfer or no transfer….
Barriers • Practice patterns • Financial • Liability • Those old things….
Until that happens…. • Preplanned action paths • Transfer emergently IV lytic candidates • -lyse them there…. • Basilar artery occlusion • Others - select • younger? • co-morbidies
ED and Hospital Capacity • Real issues with ED capacities • Other real demands on time • trauma emergencies • cardiac emergencies • surgical emergencies
Waiting • Randomized studies • Multiple centers and settings • Community vs. Academic centers • Defined selection standards • Evaluation of outcomes / transparency • Rigorous evaluation of complications
Questions? www.FERNE.org huff@virginia.edu ferne_pv_2007_huff_triage _06182007_finalcd 6/6/2014 5:18 PM