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MICRONUTRIENT DEFICIENCY DISORDERS. NUTRITIONAL DEFICINCY DISORDERS. Objectives: Discuss common micronutrient deficiencies disorders. WATER-SOLUBLE VITAMINS. Water-soluble vitamins include:
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NUTRITIONAL DEFICINCY DISORDERS • Objectives: • Discuss common micronutrient deficiencies disorders
WATER-SOLUBLE VITAMINS Water-soluble vitamins include: B complex vitamins (Thiamine, Riboflavin, Niacin, Pantothenic Acid, Biotin, Vitamin B-6, Vitamin B-12 & Folic Acid) Vitamin C.
VITAMIN B1(THIAMINE) • Deficiency Symptoms: • Dry Beriberi: • Weakness; peripheral neuropathy; loss of reflexes; ataxia; weight loss; • Wet Beriberi: • oedema; dyspnea; heart failure;
RIBOFLAVIN(VITAMIN B 2) • Deficiency Symptoms: • Ariboflavinosis; • sore throat; angular stomatitis; glossitis (magenta tongue); seborrheic dermatitis; normochromic, normocytic anemia
NIACIN (VITAMIN B 3) • Deficiency Symptoms: • Pellagra: • Photosensitive dermatitis on light-exposed areas; • Diarrhoea;stomatitis; • neurological symptoms (depression, headache, fatigue, and loss of memory - dementia)
VITAMIN B 6 • Deficiency Symptoms: • Seborrheic dermatitis, microcytic anemia, epileptiform convulsions
VITAMIN B7(BIOTIN) • Deficiency Symptoms: • Dermatitis, conjunctivitis, alopecia, and central nervous system abnormalities (depression, lethargy)
VITAMIN B9(FOLIC ACID) • Deficiency Symptoms: • MacrocyticAanemia(weakness, fatigue, difficulty concentrating, irritability, headache, palpitations, shortness of breath)
VITAMIN B 12 • Deficiency Symptoms: • Macrocytic Anemia; • Neurologic manifestations (sensory disturbances in the extremities, abnormalities of gait); • Cognitive changes (loss of concentration; memory loss); • Visual disturbances, insomnia, impotency, and impaired bowel and bladder control.
FAT-SOLUBLE VITAMINS • Fat-soluble vitamins are absorbed through the intestinal tract with the help of lipids (fats). • Fat-soluble Vitaminsrequirebile acids to absorb fat-soluble vitamins. • Because they are more likely to accumulate in the body, they are more likely to lead to hypervitaminosis than are water-soluble vitamins. • Fat-soluble vitaminsinclude vitamins A, D, E, K.
VITAMIN A • Deficiency Symptoms: • Clinical: Night blindness; total blindness • Subclinical:May increase risk for respiratory and diarrheal infections; decrease growth rate; slow bone development; and decrease likelihood of survival from serious illness
VITAMIN K • Deficiency Symptoms: • Increase in prothrombin time; in severe cases, hemorrhagic events
VITAMIN E • Deficiency Symptoms: • Nerve degeneration in hands and feet
CLASSIFICATION OF MINERALS There are two kinds of minerals: Major or Macromineralsare minerals your body needs in larger amounts. They include calcium, phosphorus, magnesium, sodium, potassium, chloride and sulfur. Trace minerals are required in small amounts. These include iron, manganese, copper, iodine, zinc, cobalt, fluoride and selenium.
IRON DEFICIENCY • Deficiency Symptoms: • Anemia, tiredness, weakness, dyspnea, , dysphagia, kolynochia , decreased work performance, impaired learning abilities, occasionally pica
IODINE Function: Component of the thyroid hormones thyroxine (T4) and triiodothyronine (T3)
IODINE DEFICIENCY DISORDERS(IDDs) • Deficiency Symptoms: • Mental retardation, hypothyroidism, goiter, cretinism, and varying degrees of other growth and developmental abnormalities
IODINE DEFICIENCY DISORDERS • Population effects of severe iodine deficiency, termed Iodine Deficiency Disorders (IDDs), include: • Hypothyroidism, • Endemic goiter, • Cretinism, • Decreased fertility rate, • Increased infant mortality, • Mental retardation and varying degrees of other growth and developmental abnormalities
ZINC DEFICIENCY • Deficiency Symptoms: • Growth retardation, hair loss, diarrhea, delayed sexual maturation and impotence, eye and skin lesions, loss of appetite, delayed wound healing
FLUORIDE • Deficiency: • Tooth cavities; tooth decay; loss of teeth. • Excess fluoride causes dental fluorosis DENATL CARIES DENTAL FLOUROSIS
CALCIUM DEFICIENCY • Deficiency Symptoms: • Reduced bone mass and osteoporosis