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NFNF

Symptomatic similarities. Shared pathways in ME / CFS and MS. NFNF. NFNFCentral hypomet. Central Hypometabolism Hypoperfusion Lactate Restorative gliosis.  Gray matter volume  White matter intensities  Astrocyte dysfunctions  Neuroinflammation. Neuro-cognitive symptoms

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NFNF

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  1. Symptomatic similarities Shared pathways in ME / CFS and MS NFNF NFNFCentral hypomet • Central Hypometabolism Hypoperfusion • Lactate • Restorative gliosis Gray matter volume White matter intensities Astrocyte dysfunctions Neuroinflammation Neuro-cognitive symptoms Central fatigue Sleep disorders PEM Autonomic symptoms Disabling fatigue (muscle) Mitochondrial & energetic disorders Secondary autoimmunity Damage by O&NS to Lipids and proteins NFNF • PICs • Th1 + Th2 • O&NS • antioxidants • NF-κB, Cox2 • B cells • Th17 + Treg NKCA Infections Viral and bacterial infections Psychosocial stressors NFNF TLR4 FOXp3 Treg

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