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Nompilo Study: Results of Evaluation. Lisa M. Butler, PhD, MPH Division of General Pediatrics, Boston Children ’ s Hospital Department of Pediatrics, Harvard Medical School Presenting on behalf of the Nompilo Study Team: C. Horwood, W. Ngidi, M. Grant, J. Reddy, P. Barker, and N. Rollins.
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Nompilo Study: Results of Evaluation Lisa M. Butler, PhD, MPH Division of General Pediatrics, Boston Children’s Hospital Department of Pediatrics, Harvard Medical School Presenting on behalf of the Nompilo Study Team: C. Horwood, W. Ngidi, M. Grant, J. Reddy, P. Barker, and N. Rollins
Implementing integrated community case management training & QI support to CHWs: • Is it feasible? • Does it lead to gains in CHW knowledge, self-efficacy and practice? • What is the effect on infant feeding practices, and uptake of PMTCT and MCH services? Research Questions
Setting and Design • Setting: • Ugu District, KwaZulu Natal, South Africa • Design: • Cluster randomized controlled trial • CHW supervisors (N=30), CHWs (N=120) • Mothers: ~8 mothers per CHW pre & post intervention
Participants and Timelines • CHW: • > 18 years old • Grade 9 education or greater • Employed by Department of Health to provide home support to pregnant women, mothers and children in Ugu District, SA • Mothers • > 18 years old • Delivered live-born infant in past 12 months • Reside in household assigned to participating CHW CHW: Baseline 6 Months 12 Months Pre-Intervention Post-Intervention Mothers:
Analytic Approach • Mixed-effects models • Interaction of treatment group with visit month tested for differences in rate of change between groups
Self Efficacy • Significantly improved self efficacy at 6 and 12 months • (intervention vs control CHWs): • Talking to a pregnant woman about HIV • Advising a pregnant woman about her own nutrition • Assisting a mother with breastfeeding • Explaining services available for PMTCT • Doing a postnatal visit to check the mother’s health & newborn baby • Recognizing danger signs in pregnancy, newborn or postpartum mother
CHW Knowledge P<0.0001 P=0.28 P<0.0001 Percent Correct
Exclusive Breastfeeding in First 6 Weeks P = 0.15 P = 0.02 N=298 N=305 N=256 N=231
Care Seeking P=0.16 P=0.02 P=0.33 P=0.02 Did not seek care for self when needed in prior 6 months Did not seek care for child when needed in prior 6 months
Receipt of ANC, PNC, HIV and PMTCT services (post-intervention)
Summary • Compared to CHWs in control arm, CHWs in intervention arm: • Significantly greater level of self-efficacy • Significantly greater level of HIV and MCH-related knowledge • Knowledge regarding HIV/MCH content sustained over time • Compared to mothers in control catchment, mothers in intervention arm: • Reported more frequent CHW visits and discussion about HIV/MCHN • Significant improvement in exclusive breastfeeding in first 6 weeks • Significant improvement in care-seeking for mothers and infants • No change in receipt of HIV testing or receipt of PMTCT services – but prevalence overall was very high
Conclusions • Training approach and materials were effective in knowledge transfer and highly appreciated even though demanding; • QI supervision and support of CHWs was feasible and valued; • Improved CHW knowledge, self-efficacy and practices were sustained over time; • Some maternal behavior change observed, despite short period of intervention
Nompilo Study Team • World Health Organization • Dr. Nigel Rollins • Institute for Healthcare Improvement • Dr. Pierre Barker • Dr. Kedar Mate • Boston Children’s Hospital • Dr. Lisa M. Butler • 20,000+ Partnership • Dr. Jennifer Reddy (PI-intervention) • WilbrodaNgidi • KhumbuzileSishi • Ellen Ntswe • Lorraine Mkhize • Sandra Reid • Centre for Rural Health, U. KwaZulu-Natal • Dr. Christiane Horwood (PI-evaluation) • Merridy Grant • Lyn Haskins • SifisoPhakathi • NtokozoMntambo • Rosemary Brown
Acknowledgements • Lenore Spies, Nutrition Manager, KwaZulu-Natal Department of Health • Janet Dalton, KwaZulu-Natal Primary Healthcare Manager • Victoria Mubaiwa, Maternal and Child Health Director, KwaZulu-Natal Department of Health • Dr. Charles McCulloch, University of California San Francisco • Dr. Henry Feldman, Boston Children’s Hospital • Funders: • US Centers for Disease Control and Prevention • World Health Organization