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12-3 DNA Replication. Federoff. Eukaryotic DNA Replication. Step 1 – Helicase unwinds and unzips the DNA molecule. Step 2 – DNA Polymerase adds on complementary nucleotides in a 5’ to 3’ direction.
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12-3 DNA Replication Federoff
Eukaryotic DNA Replication • Step 1 – Helicase unwinds and unzips the DNA molecule.
Step 2 – DNA Polymerase adds on complementary nucleotides in a 5’ to 3’ direction.
Step 3 – The lagging strand continues to replicate in fragments instead of continually like the leading strand.
Step 4 – Since the fragments still aren’t joined, the enzyme ligase, joins the fragments.
Step 5 – As replication continues, the leading and lagging strand twist back into their helical form.
Telomeres • Are the tips of chromosomes that make it less likely important genes will be lost with replication.
Prokaryotic DNA Replication • Starts at a single point, and proceeds in 2 directions until the entire chromosome is copied.
Prokaryotic vs. Eukaryotic • DNA Replication • DNAMovie • Prokaryotic DNA Replication