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Particle Size Sizing Technique 3: Laser Diffraction Photon Correlation Spectroscopy. Kausar Ahmad Kulliyyah of Pharmacy, IIUM http://staff.iiu.edu.my/akausar. Light Scattering. Reflected. When light strikes a particle, the light is then scattered in all direction. Diffracted. Refracted.
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Particle Size Sizing Technique 3: Laser Diffraction Photon Correlation Spectroscopy Kausar Ahmad Kulliyyah of Pharmacy, IIUM http://staff.iiu.edu.my/akausar Physical Pharmacy 2
Light Scattering • Reflected When light strikes a particle, the light is then scattered in all direction. • Diffracted Refracted Physical Pharmacy 2
Light scattered Physical Pharmacy 2
Scattering Intensity Physical Pharmacy 2
Static Light Scattering Physical Pharmacy 2
Particle Sizing by Laser Diffraction Physical Pharmacy 2
Mie TheoryApplication for particle size analysis Physical Pharmacy 2
Laser Diffraction Configuration Physical Pharmacy 2
Laser Diffraction Sizing Principle Physical Pharmacy 2
Examples Physical Pharmacy 2
Dynamic Light ScatteringA.k.a. Photon Correlation Spectroscopy Physical Pharmacy 2
DLS Principle Physical Pharmacy 2
PCS setup Physical Pharmacy 2
Characteristics of PCS/DLS Physical Pharmacy 2
Laser Source for DLS Physical Pharmacy 2
Factors influencing scattering intensity Physical Pharmacy 2
References http://www.photocor.com/photon_correlation_spectroscopy.htm SD Duke, RE Brown, EB Layendecker, “Calibration of spherical particles by light scattering”, Duke Scientific Corporation, Technical Note-002B, May 15, 2000. Physical Pharmacy 2