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Meta-Analysis ICU Intensive Insulin

Meta-Analysis ICU Intensive Insulin. Includes NICE-SUGAR 90 day mortality—no overall effect (pooled RR 0.93) 26 trials (n=13,567) ↑ Risk hypoglycemia ( RR 6.0) 14 trials (n=12,347) Benefit surgical ICUs (RR 0.63) 5 trials ( n=1,972 ) Majority VBG SICU study

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Meta-Analysis ICU Intensive Insulin

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  1. Meta-Analysis ICU Intensive Insulin Includes NICE-SUGAR • 90 day mortality—no overall effect (pooled RR 0.93) • 26 trials (n=13,567) • ↑ Risk hypoglycemia (RR 6.0) • 14 trials (n=12,347) • Benefit surgical ICUs (RR 0.63) • 5 trials (n=1,972) • Majority VBG SICU study • No benefit medical/mixed ICUs (RR 1.00) Griesdaleet al., Can Med Assoc J. 2009;180:821

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