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Data Acquisition and Analysis for Sleep Architecture Study

This study focuses on acquiring and analyzing sleep data, including EEG, EMG, EOG, EKG, pH, respiratory rate, and oxygen saturation, to investigate the effects of GERD on sleep patterns. It explores the relationship between reflux events and sleep stages, as well as the impact of fundoplication on sleep disruptions in GERD patients. The research is conducted at Vanderbilt Medical Center, integrating questionnaire responses, pH data, and sleep records for comprehensive analysis using Graphical and Statistical tools in Matlab.

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Data Acquisition and Analysis for Sleep Architecture Study

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  1. Data Acquisition and Analysis for Sleep Architecture Study Andrew Myers Ross Fuller Advisor: Dr. John Cohen Special Thanks to Dr. Paul Harris

  2. Objectives • Sleep Study Data Acquisition • EEG, EMG, EOG, EKG, pH, Respiratory Rate, Oxygen Saturation • Conversion of pH data • Event recognition (pH < 4) • Data Analysis, Presentation • Graphical and Statistical analysis in MatLab

  3. GERD is a common disorder... • 40% of Americans suffer monthly. • 7% of Americans suffer daily. • 25% of Americans take an antacid >2x/month • It is the most common acid-related disorder. • It is becoming more common as the population ages.

  4. What is not known? • The exact relationship between reflux events and sleep stage in normal volunteers and GERD patients. • How fundoplication affects objective sleep patterns in patients with GERD.

  5. Fundoplication

  6. The Sleep Study • The effects of fundoplication on subjects experiencing sleep disruption due to nocturnal gastroesophageal reflux disorder (GERD) • Conducted in a clinical setting at the Vanderbilt Medical Center’s General Clinical Research Center

  7. Electrode and Probe Placement

  8. Analysis • Esophageal pH data downloaded • Sleep data interpreted by neurologist (blinded) • Questionnaire, pH, sleep data integrated on database

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