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SNPs that result in STOP codons

SNPs that result in STOP codons. Human nonsense SNPs. 805 nonsense SNPs from dbSNP were tested Looked at SNPs that introduced a STOP. Genotyped 1,536 SNPs in 1,151 individuals HAPMAP + HGDP-CEPH 56 geographically diverse populations 22 CEPH (European), 23 Yoruba (Nigeria),

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SNPs that result in STOP codons

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  1. SNPs that result in STOP codons

  2. Human nonsense SNPs 805 nonsense SNPs from dbSNP were tested Looked at SNPs that introduced a STOP. Genotyped 1,536 SNPs in 1,151 individuals HAPMAP + HGDP-CEPH 56 geographically diverse populations 22 CEPH (European), 23 Yoruba (Nigeria), 23 CHB (Han Chinese), 23 LWK (Kenya) 169 nonsense SNPs were variable.

  3. Four way Venn: A, V, W and CT A,V A,V,W V,W V A,V,C All V,W,C V,C A,P A,W,C W,C C A A,W W

  4. Four way Venn: A, V, W and P A,V A,V,W V,W V A,V,P All V,W,P V,P A,P A,W,P W,P P A A,W W

  5. Prioritization for careful analysis

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