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Characterization of Novel Electronic Brachytherapy System using Geant4 Monte Carlo

Explore the characterization of a novel electronic brachytherapy system through Monte Carlo simulations with experimental verification. Investigate beam quality, HVL, attenuation curve, photon spectrum, 2-D dose distribution, and factors affecting beam quality.

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Characterization of Novel Electronic Brachytherapy System using Geant4 Monte Carlo

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  1. Geant4 Monte Carlo Characterization of Novel Electronic Brachytherapy System Derek Liu E. Poon, M. Bazalova, B. Reniers, M. Evans J. Seuntjens, T. Rusch*, F. Verhaegen McGill University * Xoft, Inc.

  2. Axxent Miniature X-ray Tube

  3. Project Objectives • Characterize x-ray tube • Monte Carlo with experimental verification • Beam quality • HVL • Attenuation curve • Photon Spectrum • Spectrum • 2-D Dose distribution • Gafchromic film in Lucite Phantom

  4. NE 2571 farmer 2 mm Pb collimator 0.5 cm aperture Src-collimator: 1” Src-Al foil: 2” Src-detector: 10” Attenuation Curve • Output fluctuation Output monitor • Beam hardening Chamber response • Scatter Subtract scatter

  5. Amp-Tek CdTe 1 mm Crystal 4 mil Be Window 2 mm W collimator 2 mm aperture Src-CdTe: 1.5 m Spectrum • Air attenuation Attenuation correction • Detector response Stripping procedure • Energy Calibration 31.0 keV Ba-133 decay 14.9 keV Yttrium K-alpha

  6. Why use Geant? Complex geometry Low energy physics C++ Coding flexibility Geometry Tip thickness 0.2 mm Transmission Tungsten target thickness 0.7 um 2 mm water Geant 4.8.1

  7. Geant 4 Bremsstrahlung Production Bremsstrahlung mean free path Bremsstrahlung angular distribution

  8. Geant 4 Bremsstrahlung Production

  9. Source to Source Variation

  10. Comparison between Measured Spectra and Geant

  11. Source to Source Variation

  12. Aging Effects

  13. Gafchromic EBT films Lucite Phantom 2-D Dose Distribution • Src parallel to film • Src-film: 1.5 cm • Exposure time: 5 min • Max dose: 5 Gy • Calibration Ir-192 calibrated in water • Film scanning Document scanner • Image registration Matlab correlation routine

  14. Gaf EBT in Lucite: Relative Dose distribution at 1.5cm

  15. Conclusion • Geant4 Bremsstrahlung production comparable with EGS • Angular distribution • Bremsstrahlung mean free path • Bremsstrahlung spectrum • Spectral measurements • Spectra in agreement with Geant4 • Attenuation curve measurements • HVL in agreement with spectral HVL and Geant4 • Observed factors affecting beam quality • Source variation • Aging effect • Dose distribution measurements • General agreement with Geant4 • Deviation in forward and aft directions

  16. Acknowledgement • This project is partially funded by Xoft, Inc. • CdTe spectrometer funded by Research Institute of MUHC

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