APRU New Initiatives/ Open Forum Session Henry T. Yang Chancellor UC Santa Barbara

APRU New Initiatives/ Open Forum Session Henry T. Yang Chancellor UC Santa Barbara

“Fifty years ago, there was no Silicon Valley. Thirty years ago, there was no biotech industry. Ten years ago, there was no Internet. Who knows what new enterprises will be created or what medical breakthroughs will result because of our institutes? But this we do know: breakthroughs will occur.” — Former Governor Gray Davis, State of the State Address, January 2000

“You rarely find the most important things by deliberately looking for them.” — Joshua Lederberg, 1958 Nobel Laureate

California Institutes for Science & Innovation • California NanoSystems Institute (CNSI) –UCLA, UC Santa Barbara • California Institute for Quantitative Biomedical Research (QB3) – UC San Francisco, UC Berkeley, UC Santa Cruz • California Institute for Telecommunications and Information Technology (Cal-IT²) – UC San Diego, UC Irvine • Center for Information Technology Research in the Interest of Society (CITRIS) – UC Berkeley, UC Santa Cruz, UC Davis, UC Merced

California Institutes for Science & Innovation • $100 million from the State for each of the four Institutes • Required 2-to-1 matching funds from non-State sources (industry, foundations, federal government, private gifts) • State funding for operating budget: $2.4 million per Institute (current year)

California NanoSystems Institute UC Santa Barbara • To be completed in January 2006 • 61,994 assignable square feet • $53 million

California NanoSystems Institute UC Santa Barbara

The Science & Technology of Nanosystems • The Software of Biology • Manufacturing from the Bottom Up • Molecular Imaging for Medicine • Molecules, Spins, and Computers • Photons, Electrons, and Information • Laboratories on the Head of a Pin

CNSI: Creating a New Infrastructure and Paradigm for Scientific Innovation Integration Collaboration Incubation

Institute for Collaborative Biotechnologies Mission: The mission of the new Institute for Collaborative Biotechnologies (ICB) is to provide national leadership in frontier research at the interface between biotechnology and engineering in order to harness complex biological mechanisms for the development of revolutionary approaches to advanced sensors; electronic, optical, and magnetic materials; information process and network control systems to enhance the effectiveness of the Army. The motivating vision is to provide the Army with full-spectrum access to high-impact biotechnologies that will accelerate the pace of Army transformation.

Institute for Collaborative Biotechnologies Sensors on the antennas of this moth are capable of detecting just a single molecule of the scent released by its mate, inspiring efforts to harness the mechanisms underlying this remarkable sensitivity

Institute for Collaborative Biotechnologies The Information Processing team investigates the role of electron spin correlation in biological information transfer ICB's biotechnology develops new route to semiconductor nano-fabrication ICB researchers explore novel RNA-based technology for sensor development

Nanometer = 10-9 meters 1 Nanometer = size of three atoms

From Office of Basic Energy Sciences, U.S. Department of Energy

“The principles of physics, as far as I can see, do not speak against the possibility of maneuvering things atom by atom." — Richard Feynman, from his classic 1959 talk “There is Plenty of Room at the Bottom”

Feynman Prizes—Two Nanotechnology Challenges “It is my intention to offer a prize of $1,000 to the first guy who can take the information on the page of a book and put it on an area 1/25,000 smaller in linear scale, in such manner that it can be read by an electron microscope. And I want to offer another prize… of another $1,000 to the first guy who makes an operating electric motor—a rotating electric motor which can be controlled from the outside and, not counting the lead-in wires, is only 1/64 inch cube. I do not expect that such prizes will have to wait very long for claimants.“ — Offered by Richard Feynman in 1959; prize #1 awarded in 1960, prize #2 in 1985

First Feynman Prize - McLellan's Motor (awarded in 1960) Bill McLellan: "He'd seen a lot of cranks come in with motors who didn't understand the challenge and I brought in a big box, and he said 'Uh-oh, here's another one of them.' And then I opened my wooden box and there was my microscope, and he said 'Oh! Nobody else brought a microscope!'" "Feynman's disappointment was he didn't get the new method," says McLellan. Nevertheless, he handed over the $1,000 prize he had promised. And McLellan said it did help Feynman's goal in the longer term. Image: Caltech Archives

Feynman Grand Prize (created in 1996 by the Foresight Institute; so far unclaimed) $250,000 prize for the first persons to design and build two nanotechnology devices: • a nano-scale robotic arm • a computing device that demonstrates the feasibility of building a nanotechnology computer

“There’s Plenty of Room at the Bottom: An Invitation to Enter a New Field of Physics” Richard Feynman lecture at Caltech, 1959 The marvelous biological system The biological example of writing information on a small scale has inspired me to think of something that should be possible. Biology is not simply writing information; it is doing something about it. A biological system can be exceedingly small. Many of the cells are very tiny, but they are very active; they manufacture various substances; they walk around; they wiggle; and they do all kinds of marvelous things—all on a very small scale. Also, they store information. Consider the possibility that we too can make a thing very small which does what we want—that we can manufacture an object that maneuvers at that level!

“Nanotechnology… can lift mankind to a higher level, and give the pioneer nation an edge over all others." — Minister Mentor Lee Kuan Yew, at the Boao Forum for Asian, April 23, 2005

Thank you

APRU New Initiatives/ Open Forum Session Henry T. Yang Chancellor UC Santa Barbara