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Toluene di-isocyanate (TDI)

This toxin causes “bathtub refinisher’s lung” and is the largest recognized cause of occupational asthma. Toluene di-isocyanate (TDI). This pesticide is best known for its toxicity involving male sterility. Dibromochloropropane ((DBCP) Re: “Da Balls Can’t Produce”.

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Toluene di-isocyanate (TDI)

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  1. This toxin causes “bathtub refinisher’s lung” and is the largest recognized cause of occupational asthma

  2. Toluene di-isocyanate (TDI)

  3. This pesticide is best known for its toxicity involving male sterility

  4. Dibromochloropropane ((DBCP) • Re: “Da Balls Can’t Produce”

  5. Which solvent is associated with “degreaser’s flush” and trigeminal neuralgia?

  6. Trichloroethylene

  7. This intoxicant is a NTE inhibitor resulting in a sensory-motor neuropathy. It is linked to large outbreak of cases in 1960 Morocco but better known for its link to Ginger Jake

  8. Triorthocresyl phosphate (TOCP)

  9. What is the leading cause of lung cancer behind tobacco smoke?

  10. Radon

  11. What chemical has the smell of freshly mowed hay?

  12. Phosgene

  13. Name a metal that results in non-fibrogenic benign pneumoconiosis with exposure

  14. Tin (Stannosis) • Barium (Baritosis) • Iron (siderosis) • Calcium (Chalitosis) • Molybdenum

  15. What chemical was this worker using that resulted in his acroosteolysis

  16. Vinyl chloride

  17. What is the most common medication associated with hypersensitivity pneumonitis

  18. Nitrofurantoin

  19. Name the mushroom responsible for muscle weakness 24-72 hrs after ingestion with massive CPK elevations. • And a 25% mortality to boot!

  20. Tricholoma equestre

  21. What maternal chemical exposure may result in mental retardation and “cola-colored” discoloration at birth?

  22. PCBs • (remember Pepsi-Colored Babies)

  23. Drug Concentration Natural Log (ln) Drug Concentration Time (hrs) Time (hrs) Name the order of elimination

  24. 1st Order Elimination

  25. Which metal is radiolucent on plain film radiograph?

  26. Copper

  27. Name the structure

  28. Succimer (DMSA)

  29. What chemical uses urine hippuric acid for biological monitoring during worker exposure?

  30. Toluene

  31. What is the only organic phosphorus pesticide that possesses a significant vapor hazard (i.e., has a high vapor pressure)?

  32. Dichlorvos

  33. Which natural toxin is responsible for amnestic shellfish poisoning?

  34. Domoic acid • (think Dumb-oic acid)

  35. What is reported to be the most fatal plant species in North America (30-70% fatality rate)?

  36. Water Hemlock • Water Gate Candidate Scandal (Water hemlock, GABA, Cicutoxin, Seizures)

  37. What part of the action potential does this plant’s toxin effect?

  38. Nerium oleander • Digitalis – cardiac steroid • Increases resting potential and effects phase 4 of the cardiac cycle = increases automaticity

  39. What is the only form of poisoning caused by bacterial contamination of the food?

  40. Scombroid • (Histamine poisoning)

  41. Scombroid • (Histamine poisoning)

  42. Name the plant responsible for St. Anthony’s Fire and ergotism

  43. Claviceps purpurea

  44. Name the term for the following definition: • “The maximum concentration of a chemical to which workers may be exposed continuously for up to 15 minutes without danger to health or work efficiency and safety”

  45. STEL • (Short-term exposure limit)

  46. Which sulfonylurea is associated with SIADH and disulfiram reactions?

  47. Chlorpropramide

  48. Which antidysrhythmic has antimuscarinic properties and causes hypoglycemia in overdose?

  49. Disopyramide

  50. Name two intoxicants (there are at least 4) that produce metaphyseal bands on plain-film x-ray.

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