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ADAPTIVE CONTROL OF FED-BATCH PROCESS OF POLY -  -HYDROXYBUTYRATE ( PHB ) PRODUCTIONBY MIXED CULTURE

Institute of Control and System Research. Bulgarian Academy of Sciences. ADAPTIVE CONTROL OF FED-BATCH PROCESS OF POLY -  -HYDROXYBUTYRATE ( PHB ) PRODUCTIONBY MIXED CULTURE. Dr. Maya IGNATOVA. Prague, October, 9, 2007. Process reaction scheme. Model of the process.  2.  1.

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ADAPTIVE CONTROL OF FED-BATCH PROCESS OF POLY -  -HYDROXYBUTYRATE ( PHB ) PRODUCTIONBY MIXED CULTURE

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  1. Institute of Control and System Research Bulgarian Academy of Sciences ADAPTIVE CONTROL OF FED-BATCH PROCESS OF POLY--HYDROXYBUTYRATE (PHB) PRODUCTIONBY MIXED CULTURE Dr. Maya IGNATOVA Prague, October, 9, 2007

  2. Process reaction scheme

  3. Model of the process 2 1

  4. Defining a control marker  is the control marker

  5. 2MAX L opt The optimal value of lactate is known – by Haldane model

  6. 3. Adaptive control algorithms based on General Dynamical Model Approach ADAPTIVE CONTROL SCHEME + S + F Process model Adaptive F controller L DO  1 -2 DO* DO control S. Sensors

  7. Working program • Аcquaintwithtoolbox 'Jobcontrol' functions • Discussions about applicability of toolbox 'Jobcontrol' for control design of the considered process. • Control design applying toolbox 'Jobcontrol‘ ?

  8. Our main publications on the topic • Lyubenova V., M. Ignatova, M. Novak, Т. Patarinska, (2006), Model for Control of Fed-Batch Process for Poly--Hydroxybutyrate (PHB) Production by Mixed Culture of L. Delbrulckii and R. Eutropha, In: International Scientific Conference “Food Science, Techniques and Technologies 2006”, University of Food Technologies Plovdiv, Bulgaria, 27-28 October, V. LIII(2), 99-104. • Ignatova M., V.Lyubenova and al. (2007), Indirectadaptivelinearizingcontrolofaclassofbioprocesses – Estimatortuningprocedure, Journal pf Process Control (2007), doi:10.1016/j.jprocont.2007.06.00. • Lyubenova V., M. Ignatova, M. Novak, Т. Patarinska (2007), Reaction rates estimators of Fed-Batch Process for Poly--hydroxybutyrate (PHB) Production by Mixed Culture, Biotechnology&BioE, (Sofia), 21(1) (2007), pp. 113-116. • Ignatova M., V.Lyubenova, (2007), Adaptive control of fed-batch process for poly--hydroxybutyrate production by mixed culture, Proceedings of Bulgarian Academy of Sciences, V. 60 (5), pp 517-524. • Ignatova M., V. Lyubenova (2007). Control of class bioprocesses using on-line information of intermediate metabolite production and consumption rates, International Conference “Agricultural and Food Sciences, Processes and Technologies”,, Acta Universitatis Cibiniensis, Series E: Food Technology, I.S.S.N. 1221-4973, (2007), Sibiu, Romania.

  9. Acknowledgments This work was supported by : • The joint project in framework of bilateral agreements between Bulgarian Academy of Sciences and Academy of Science of Czech Republic.

  10. THANKS FOR YOUR ATTENTION!

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