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QMS: A Better Magnetic Method for the Sorting of Human Stem Cells

QMS: A Better Magnetic Method for the Sorting of Human Stem Cells. Lisa M. Reece School of Veterinary Medicine Dept. of Basic Medical Sciences Birck Nanotechnology Center 06/03/2010. Why Do We Need to Sort Stem Cells ?. Stems cells used to repair damaged tissue

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QMS: A Better Magnetic Method for the Sorting of Human Stem Cells

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  1. QMS:A Better Magnetic Method for the Sorting of Human Stem Cells Lisa M. Reece School of Veterinary Medicine Dept. of Basic Medical Sciences Birck Nanotechnology Center 06/03/2010

  2. Why Do We Need to Sort Stem Cells? • Stems cells used to repair damaged tissue • Transplanting stem cells into damaged area • Coax stem cells present in body to produce new tissue • Pure sorting populations yield more success with stem cell transplants

  3. Magnetic Marking Instead of dyes, the identifying proteins can be marked with tiny magnetic spheres. Magnetic Separation A magnet then separates the marked and unmarked cells.

  4. Quadrupole Magnetic Sorter (QMS) Reece et al. SPIE, 7568-73, 2010

  5. QMS Sorting Schema

  6. Acknowldegements IKOTECH, LLC David Kennedy Byron Guernsey Techshot, Inc. Paul Todd Purdue University James F. Leary Lehanna Sanders Stephen Wereley Supported by National Science Foundation (DMI-0319508), National Institutes of Health (1 RH43 HL074606), National Aeronautics and Space Administration (NAS9-97027), 21st Century Research and Technology Fund, State of Indiana

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