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Mendelian Genetics. Genetics: The Scientific Study of Heredity. Mendel –Austrian Monk Born 1822 Spent years studying science and mathematics Worked at a Monastery and taught High School. Also in charge of the monastery garden- This work is where Mendel developed his theories on Genetics.
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Genetics: The Scientific Study of Heredity • Mendel –Austrian Monk • Born 1822 • Spent years studying science and mathematics • Worked at a Monastery and taught High School. • Also in charge of the monastery garden- This work is where Mendel developed his theories on Genetics
Sexual Reproduction • Mendel understood that pollen contained the male reproductive cells and that the female portion of the flower produces the egg. • When the male and female sex cells are joined together this is called fertilization and a seed is formed. http://anthro.palomar.edu/mendel/mendel_1.htm
Pea Plants: • Pea plants can self-pollinate-meaning the pollen of a plant can fertilize the same flower (Inbreeding). This produces a seed with the same characteristics as the parent plant (true-breeding/homozygous). • These plants would produce only green seeds only yellow seeds, only tall seeds,etc
Cross-Pollination • Mendel wanted to produce seeds by joining male and female reproductive cells from different plants-so he dusted pollen from one plant on to another to cross-pollinate. • This can also be done naturally by pollinators such as bees. http://www.fs.fed.us/wildflowers/pollinators/images/xpollination_ani.gif http://www.dkimages.com/discover/previews/955/738361.JPG
Data/ObservationPollen Pictures Day 2Lilium oriental (+) control After 120min ~100 µm Pollen tube Picture by Charles Beckius
Genotype – the actual codes for a trait ex. BB,Bb,bb • Phenotype- the traits seen
Dominant vs. Recessive • Principle of dominance states that some alleles are dominant and others are recessive. • Capitol Letters =dominant traits=if gene is present, trait will always be seen. • Lower case letter =recessive traits=hidden traits. BB x bb = Bb
True-breeding/homozygous • BB or bb pure characteristics from having all the same alleles
Hybrids/heterozygous • The offspring of crosses between parents with different traits are called hybrids. BB x bb = Bb brown x blue Hybrid brown
Traits • Mendel studied 7 different pea plant traits. • Seed shape- round vs. wrinkled • Seed color – yellow vs. green • Seed coat color- gray vs. white • Pod shape- constricted vs smooth • Pod color green vs. yellow • Flower position – axial vs. terminal • Plant height- short vs. tall
haploid Diploid haploid + - haploid http://www.mansfieldct.org/schools/mms/staff/hand/genpunnet1.htm
Mendel’s P, F1, and F2 Generations • P-parent generationTT x tt T T t Offspring of the P generation is the F1 generation Tt Tt Tt Tt t Cross the F1-1st filial generation Tt x Tt T t T TT Tt To get the F2 “filial generation t Tt tt
MENDEL's first law is the principle of uniformity. It says that, if two plants that differ in just one trait are crossed, then the resulting hybrids will be uniform in the chosen trait. http://dwb.unl.edu/Teacher/NSF/C08/C08Links/www.rrz.uni-hamburg.de/biologie/b_online/e08/08a.htm
MENDEL's second law is the principle of segregation. It states that the individuals of the F2 generation are not uniform, but that the traits are segregated
MENDEL's third law is also called the principle of independent assortment. It says that every trait is inherited independently of the others and it thus covers the case that new combinations of genes can arise, which were not existing before. We know today that this principle is just valid in the case of genes that are not coupled, i.e. that are not located at the same chromosome.
MENDEL's 4th law is also called the principle of attraction. It says that since every sperm and egg are polar and that since sperm are slightly positive and ova is slightly negative they are always attracted to each other. In addition some alleles are also polar which increase the combination of certain characteristics combining together. For example blonde hair and blue eyes are more likely to developed together since those alleles are polar opposites. However this only occurs if the alleles are not located at the same chromosome.
Incomplete Dominance • http://dwb.unl.edu/Teacher/NSF/C08/C08Links/www.rrz.uni-hamburg.de/biologie/b_online/ge08/01.gif
In-complete dominance
Co-Dominance http://media.nasaexplores.com/lessons/02-064/images/image2.jpg
Dihybrid Cross http://bio.winona.edu/berg/ILLUST/mend7.gif
iA iB io io http://www.biologycorner.com/resources/bloodtype_chart.gif
http://www.bioweb.uncc.edu/1110Lab/notes/notes1/images/lab7.h28.jpghttp://www.bioweb.uncc.edu/1110Lab/notes/notes1/images/lab7.h28.jpg
Sex-Linked Traits http://www.biologycorner.com/bio2/specialgenetics.html http://www.uni.edu/walsh/xlink2.gif
Pedigree http://www.koshland-science-museum.org/img/sub/teachers/webquest-gd-007.jpg