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Hypothalamus – Pituitary – Adrenal Axis Rough Overview. hypothalamus (in brain). when needed, the hypothalamus sends out CRH, which activates the pituitary. CRH Corticotropin Releasing Hormone. pituitary gland. in response, pituitary sends out ACTH, which goes to the adrenal glands. ACTH
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Hypothalamus – Pituitary – Adrenal Axis Rough Overview hypothalamus (in brain) when needed, the hypothalamus sends out CRH, which activates the pituitary CRH Corticotropin Releasing Hormone pituitary gland in response, pituitary sends out ACTH, which goes to the adrenal glands ACTH adrenocorticotropic hormone adrenal gland specifically adrenal cortex in response, adrenal cortex sends out cortisol, which has many effects in many different parts of the body. cortisol body many effects on many different systems, including blood vessels, digestive system, kidneys, etc.