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Hesperidin

Hesperidin is one of the major constituents found abundantly in citrus fruits. It is a bioflavonoid that is believed to play a beneficial role in a number of different body systems. For more information on the general benefits of bioflavonoids, please see our Bioflavonoids article. Supplementation with hesperidin has been shown to have a number of benefits for overall health

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Hesperidin

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  1. Hesperidin The bioflavonoid that can help to protect the brain, liver, and cardiovascular system while also helping menopausal symptoms and fighting cancer … Hesperidin is one of the major constituents found abundantly in citrus fruits. It is a bioflavonoid that is believed to play a beneficial role Brain and Liver Health in a number of different body systems. For more information on the general benefits of bioflavonoids, please see our Bioflavonoids article. Supplementation with hesperidin has been shown to have a number of benefits for overall health. Antioxidant – Hesperidin is an antioxidant that can help to protect the body against free radical damage. Free radicals are unstable molecules with an unpaired electron that are extremely reactive, and damage surrounding cell membranes, fats, and fat-soluble vitamins and nutrients. We encounter free radicals through environmental exposures, such as cigarette smoke, air pollution, processed foods, and ultraviolet radiation from the sun (UV rays). The antioxidant properties of hesperidin have been found to especially protect neurons in the body against oxidative damage. Protecting neurons allows hesperidin to help protect the brain cells and to maintain healthy mental functioning. The potent antioxidant ability provided by hesperidin also allows it to protect the liver against damage caused by toxic chemicals and pollutants. For more information, please see our articles on Antioxidants, Neurological Disorders, and Liver Health. Circulation and Cardiovascular Health One study found that people with extreme cold sensitivity can be treated with oral hesperidin supplementation. It was found that hesperidin promoted dilation of the blood vessels along the exterior of the body, allowing for a better circulation of heat. Another study found that hesperidin promotes the production of nitric oxide (NO), a substance that has been shown to relax the blood vessels. Dilation of the blood vessels can help to reduce blood pressure. When combined with diosmin, hesperidin is commonly used to treat hemorrhoids and leg ulcers. It has been found to reduce the inflammatory response in chronic venous insufficiency. For more information, please see our article on Poor Circulation. Glucosyl Hesperidin – Protecting against arteriosclerosis A particular sub-type of hesperidin called glucosyl hesperidin has been shown to lower triglyceride levels in people with excessively high levels in their blood. It has also been shown to slightly lower LDL (“bad”) cholesterol in those with imbalanced cholesterol levels. Both of these can help to reduce the risk of developing arteriosclerosis and cardiovascular disease. For more information on balancing cholesterol and blood triglycerides, please see our articles on Cholesterol and Arteriosclerosis. Menopause Many healthcare practitioners use hesperidin to help with the symptoms of menopause. When combined with vitamin C, hesperidin supplementation has been shown to help reduce the frequency and severity of hot flashes. It has also been found to have a gentle sedative action, which can help to relieve the mental-emotional symptoms of menopause, particularly anxiety. One study found that hesperidin supplementation also reduces the amount of bone density loss during aging, thus potentially helping to prevent osteoporosis. For more information on treatment and prevention, please see our Menopause and Osteoporosis articles. Cancer In recent research, a metabolite of hesperidin called hesperetin has been shown to prevent tumour cell growth and also to prevent hormone production. This gives it great potential for further study in the treatment of breast cancer and other hormone- sensitive cancers. This may also be how it reduces menopausal symptoms, although that hasn’t yet been established. The direct anti-cancer activity of hesperetin has also been seen in colon cancer cell lines in the laboratory. For more information on potential treatments, please see our Cancer article. How can I take hesperidin? Hesperidin is often found in combination with other nutrients for specific functions. It can be found in formulas for: detox, circulation, cardiovascular, menopause, and cancer. It is often combined with vitamin C and diosmin. For the treatment of hemorrhoids 150mg of hesperidin (with 1350mg of diosmin) twice daily for four days, followed by 100mg of hesperidin (with 900mg of diosmin) twice daily for three days. Maintenance treatment for hemorrhoids is 50mg of hesperidin (with 450mg diosmin) twice daily for 3 months. To treat leg ulcers caused by poor blood circulation, the dose is 100mg of hesperidin (with 900mg diosmin) daily for up to 2 months. For other treatment approaches, follow the recommended dosage provided by the manufacturer.

  2. Nutritional Information Hesperidin – Quick Facts Parts Used · Citrus Fruits Applications · Toxic Build Up, Brain Health, Poor Circulation, Venous Ulcers, Hemorrhoids, High Blood Pressure, Cardiovascular Disease, Arteriosclerosis, Dyslipidemia, Menopause, Osteoporosis, Cancer Optimum Dosage · Typical Dose: 100mg (Combined With 900mg Diosmin) Daily. · Hemorrhoid Dose: 150mg (With 1350mg Diosmin) Twice Daily For 4 Days, Then 100mg (With 900mg Diosmin) Twice Daily For 3 Days. (Clinical Doses May Vary As Recommended By Your Healthcare Practitioner). Works Well With · Vitamin C, Diosmin, And Bioflavonoids Important Information Click For Products · There Are No Safety Issues With The Use Of Hesperidin When Continued For Less Than Six Months. Safety For Longer Use Is Not Yet Established. · Some People Experience Stomach Pain, Diarrhea, And Headache With Hesperidin Supplementation. All Articles Copyright Of National Nutrition 2001-2012. For Informational Purposes Only. Please Consult Your Health Care Practitioner Before Taking Natural Health Care Products. Click Here For Full Disclaimer.

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