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CTGAGTC

CTGAGTC. Brain. Liver. Muscle. CpG Island. Ac. Ac. Ac. Active. Inactive. Ac. MeCP2. Ac. GC. GC. CG. CG. CG. CG. GC. GC. GC. GC. CG. CG. Brain. Liver. Muscle. m. C. m. C. A. A. C. C. T. T. G. G. p. 5. 3. -. /. -. p. 5. 3. -. /. -. M. T. a. s.

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CTGAGTC

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  1. CTGAGTC

  2. Brain Liver Muscle

  3. CpG Island

  4. Ac Ac Ac Active Inactive

  5. Ac MeCP2 Ac

  6. GC GC CG CG CG CG GC GC GC GC CG CG

  7. Brain Liver Muscle

  8. m C m C A A C C T T G G p 5 3 - / - p 5 3 - / - M T a s e - / -

  9. Ac Ac Ac HAT

  10. Ac Ac Ac HAT

  11. Ac Ac Ac HDAC HAT

  12. HDAC HAT

  13. I B I B III 4 Me Ac 4 Demethylation H3 H4 H4 H3 Me 9 9 Me Ac

  14. Demethylation

  15. 104 I Non e 101 II Repressor 102 II I M e M e 10-1 I V +

  16. M S G2 G1 3 h 5 h 7 h 9 h 11 h G2 M S G1

  17. M G2 G1 S Replication time

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