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Study of Metabolic Syndrome in children in KY. Sathya S Krishnasamy MD Division of Endocrinology,Diabetes & Metabolism. Metabolic syndrome ( MetS). Abdominal obesity, dyslipidemia , hypertension, glucose intolerance. 25% of the world’s adults have MetS
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Study of Metabolic Syndromein children in KY Sathya S Krishnasamy MD Division of Endocrinology,Diabetes & Metabolism
Metabolic syndrome (MetS) • Abdominal obesity, dyslipidemia, hypertension, glucose intolerance. • 25% of the world’s adults have MetS • People with MetS are twice as likely to die from, and 3x times as likely to have CVD . • People with MetShave a 5x- greater risk of developing type 2 diabetes • Up to 80% of the 200 million people with diabetes globally will die of cardiovascular disease IDF.org,Grundy S Lancet 2005
ATP III: The Metabolic Syndrome**Diagnosis is established when >3 of these risk factors are present JAMA, 2001;285:2486-2497
MetS in SAI, an at risk population, and focus on their children
Results and Conclusion SAI children with one parent with the MetS had 24% lower levels of SHBG that increased to 55% if both parents were affected. Characteristics of the MetS are present in children of SAI origin as early as 5-9 years of age. SHBG may prove to be a useful marker for MetS in preadolescent children