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Caption: Real time PCR analysis of GFR alpha 1 (top), alpha 3 (middle), and alpha 4 (bottom) gene expression in normal pituitary (CON, n= 13), all pituitary tumors (TUM, n= 39), non-functioning adenomas (NFA, n= 21), functioning adenomas (FUNC, n=18), GH-secreting adenomas (GH, n=14), ACTH-secreting adenomas (n= 2), prolactin-secreting adenoma (PRL, n=1), and TSH-secreting adenoma (TSH, n=1). Data are presented as mean transcript fold changes relative to one normal control sample and normalized to GAPDH, with each bar representing the standard error of the mean (SEM). *p<0.05, ** p<0.01 (relative to control).