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Estrogen. By Christina Roth and Christina Arce. What is Estrogen. General name for a group of hormone compounds Estrone , estradiol, estriol Estrogen primarily comes from womens ’ ovaries Some estrogen is produced by other parts of the body like the liver, breasts, and adrenal glands.
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Estrogen By Christina Roth and Christina Arce
What is Estrogen • General name for a group of hormone compounds • Estrone, estradiol, estriol • Estrogen primarily comes from womens’ ovaries • Some estrogen is produced by other parts of the body like the liver, breasts, and adrenal glands. • Primary female sex hormone • Found in males, but more likely in girls • Steroid (if it is natural) • Synthetic Estrogen is non-steroidal
Function of Estrogen • Promote development and maintenance of female sexual characteristics • Breasts, widened pelvis, less facial hair, smooth skin. • Regulates menstrual cycle, prepares uterus for pregnancy
Positive or Negative Feedback • Positive • occurs at high concentrations near end of follicular phase • Positive feedback triggers the anterior pituitary to release more FSH and LH • More FSH and LH cause the ovary to produce more estrogen • Negative • Occurs during follicular phrases when estrogen levels are low
Hyper-secretion: premature sexual development (female) and infertility Hyposecretion; lack of sexual development (female), infertility, and osteoporosis Ovarian cysts Breast Cancer Weight gain secondary to insulin resistance. Fibrocystic breast disease Certain types of PMS Migraines Menstrual disturbances--irregular and heavy bleeding. Endometriosis, the uterine tissue disorder, which is helped by the use of estrogen blockers. Fibroids, a sign of excess proliferative capacity of the uterus, which may not be balanced with sufficient progesterone. Estrogen Disorders