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Mutations Foldable

Mutations Foldable. Fold 3 pieces of paper, so you have 5 layered flaps Write “ Mutations” on the top flap as a title. On each flap write:. What is a mutation? Point Mutations Chromosomal Mutations Advantages/Disadvantages Real Life Example. 1. What is a mutation?.

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Mutations Foldable

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  1. Mutations Foldable • Fold 3 pieces of paper, so you have 5 layered flaps • Write “Mutations” on the top flap as a title

  2. On each flap write: • What is a mutation? • Point Mutations • Chromosomal Mutations • Advantages/Disadvantages • Real Life Example

  3. 1. What is a mutation?

  4. (Inside) On Top Half of 1st Flap write: • Mutations- any change in DNA that may affect the expression of a gene • Proteins that produced as a result of mutations: • may fail to function • may change the phenotype of an organism • Mutations can be caused by mutagens. • Examples from the environment- UV light, chemicals, radioactive substances, X-rays

  5. (Inside) On Bottom Half of 1st Flap: Glue in the following picture & Label the following: • Strand D- DNA was mutated by UV light; circle the 5th base- it should be T but now is C • Strand H- mRNA is made from mutated DNA template during transcription; circle the 5th base- it should be A but now is G • Stand N- Polypeptide chain (amino acid sequence); circle the 2nd amino acid (THIS IS THE WRONG AMINO ACID!) • O- Mutation is seen here first; mutation causes no color pigment to occur • Flowers have no color!

  6. 2. Point Mutations

  7. (Inside) On Top Half of 2nd Flap write: • Point Mutations- a change in a specific base in the DNA that causes a “shift” in the reading frame  causes a change in codons

  8. (Inside) On Bottom Half of 2nd Flap write: TYPESGlue in the following picture & Label the following: • Circle the substitution that has occurred; next to the picture write: Substitutions occur when one base is changed • Circle the deletion that has occurred ; next to the picture write: Deletions occur when one base is removed or lost (3) Circle the insertion that has occurred ; next to the picture write: Insertions occur when one base is added to a sequence of DNA

  9. 3. Chromosomal Mutations

  10. (Inside) On Top Half of 3rd Flap write: • Chromosomal Mutations- a change in a specific segment of the DNA  both positive and negative affects • cause a protein to malfunction • cause a different protein to be made

  11. (Inside) On Bottom Half of 3rd Flap write: TYPESGlue in the following picture & Label the following: • Color the segment of DNA that has been deleted; next to the picture write: Deletions occur when a segment of DNA has been removed • Color the segment of DNA that has been inverted; next to the picture write: Inversions occur when a segment of DNA has been flipped • Color the segment of DNA that has been translocated; next to the picture write: Translocations occur when a segment of DNA has moved to a different location on another chromosome • Color the segment of DNA that has been duplicated; next to the picture write: Duplications occur when another copy of a segment of DNA is made

  12. 4. Advantages/Disadvantages of Mutations

  13. (Inside) On Top Half of 4th Flap write: ADVANTAGES • New forms of a trait • Drug resistance • Antibiotic resistance

  14. (Inside) On Bottom Half of 4thFlap write: DISADVANTAGES • Absence of a trait • Cancer • Diseases/Genetic Disorders • Sickle Cell Anemia

  15. 5. Mutations in the Human Body

  16. Examples of Disease that cause mutations Sickle Cell Anemia Next to picture: Explain the mutation

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