ENSURE PROCESS EFFICIENCY AND QUALITY IN TABLET/CAPSULE PACKAGING WITH NICHROME

1. ENSURE PROCESS EFFICIENCY AND QUALITY IN TABLET/CAPSULE PACKAGING WITH NICHROME

2. INTRO Due to the sensitive nature of products, the pharmaceutical packaging industry faces a lot of challenges. Inappropriate packaging can cause chemical alterations in the product affecting the product’s curative ability and effective performance. This is why the pharmaceutical industry is subjected to rigid packaging standards and often faces a variety of challenges.

3. CHALLENGES FOR PHARMA PACKAGING • SAFE TRANSPORTATION: • Pills and capsules are easier to handle• Liquid medication and injections, especially with fragile glass packing, are more difficult. • ACCURATE DOSAGE AND DRUG INFORMATION: • To avoid confusion and over- or under-consumption• Must contain the necessary dosage information as well as information regarding the drug's composition, expiry date, and serial/batch number to enable tracking and prevent misuse. • PROTECTING THE MEDICINAL QUALITY: • Exposure to heat and humidity can negatively impact the efficacy of pharma products• Packaging materials have to be carefully chosen so that the product's healing capability is not impaired by external factors.

4. IMPORTANCE OF PHARMA PACKAGING Regarding quality of pharma products, a WHO technical report states that in the manufacture of pharmaceutical products, quality assurance is defined as “the totality of the arrangements made with the object of ensuring that pharmaceutical products are of the quality required for their intended use”.* Packaging preserves the stability and quality of medicinal products and protects them against all forms of spoilage and tampering. All medicinal products consequently need to be 'packaged in containers that conform to prescribed standards, particularly with respect to the exclusion of moisture and light and the prevention of leaching of extractable substances into the contents and of chemical interaction with the contents.’ *(https://www.who.int/medicines/areas/quality_safety/quality_assurance/GuidelinesPackagingPharmaceuticalProductsTRS902Annex9.pdf)

5. CAPSULE PACKAGING Packaging of tablets/capsules is the science, art and technology of enclosing and protecting a product for distribution, storage, sale and use. Packaging must serve these varied requirements: Protection Information Identification Convenience Storage

6. CAPSULE PACKAGING SOLUTIONS For tablet/capsule packaging, Nichrome has tied up with reputable international majors to bring the latest, most cost-effective pharma packaging machines and integrated lines for India’s pharmaceutical industry. The solutions include: COUNTING AND FILLINGNichrome offers high speed tablet filling machines and capsule filling machines automatic. Customers can choose from separate systems that can be easily integrated into new or existing bottle packaging lines or opt for complete integrated systems. The solutions in this category include:• High Speed Counting and Feeding Systems • Bottle Filling, Capping, Labelling Systems• Desiccant Insertion, Leaflet Insertion• Integrated Lines

7. CAPSULE PACKAGING SOLUTIONS BLISTER PACKAGINGNichrome’s blister packaging machine offers a wide range of solutions: among these are PVC, PCTFE, PVDC and thermoform blisters for less sensitive products or Alu-Alu cold form blisters for Active Pharmaceutical Ingredients (APIs) that are more sensitive. TABLET TOOLINGNichrome provides tablet pressing tools, Tablet press machine spare parts, maintenance kits of pressing tools from YenerKalip of Turkey, multinational leader in tablet compression tools for the pharmaceutical industry. Yener's range of innovative, high-quality punches and dies offer the assurance of the design, product, process reliability and service required for modern pharma industries.

8. WHY NICHROME? Has joined hands with top international pharma packaging machinery manufacturers to bring the latest, most reliable pharma packaging solutions for the Indian pharma industry. Is India’s leading provider of integrated packaging solutions. At the forefront of next-gen packaging technologies since 1977 A brand trusted for its rich legacy of pioneering innovation, extensive domain knowledge and manufacturing competency in automatic packaging machines and packaging solutions in India. For enterprises big and small, for applications existing and emerging, across Food, Pharma and other sectors, offers infinite possibilities in integrated, automated packaging solutions. Partners with customers through the complete lifecycle, offering application-specific solutions, backed by dependable service and support. Based in Pune, India, Nichrome’s sales & service network spans India and the world. Presence in 45 countries and more than 8000 successful installations worldwide.

9. CONCLUSION Whether your pharma industry requires an automatic capsule machine or tablet counting and filling machine; a blister packaging system or integrated bottle filling line with capping, labelling and leaflet insertion – Nichrome is your go-to partner for packaging solutions India. Nichrome offers international technologies from global majors, backed by Nichrome’s own local expertise for installation, commissioning and after-sales service.

10. NICHROME INDIA LTD. Safire Park Galleria, 4, Pune - Mumbai Road, Shivajinagar, Pune - 411 005, India. T: +91 - 20 - 6601 1001 | F: +91 - 20 - 6601 1010 | E-mail: marketing@nichrome.com | www.nichrome.com Service Centres & Offices at: Delhi | Kolkata | Mumbai | Bangalore | Hyderabad | Chennai | Ahmedabad | Chandigarh | Kanpur ASEAN | MIDDLE EAST | SAARC | RUSSIAN FEDERATION & CIS | AFRICA | USA PACKAGING SOLUTIONS FOR: LIQUIDS | GRAINS | POWDERS | SEEDS | SNACKS | PHARMA | PERSONAL CARE Contact www.nichrome.com