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Chapter 17. Vitamins, OTC Supplements, Antidotes, and Miscellaneous Topics. Medical Foods. Not FDA approved Manufacturer may determine that medical food must have Rx to be dispensed, but no FDA review required
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Chapter 17 Vitamins, OTC Supplements, Antidotes, and Miscellaneous Topics
Medical Foods • Not FDA approved • Manufacturer may determine that medical food must have Rx to be dispensed, but no FDA review required • Used for burn victims, kidney dialysis patients, or patients with CV disease or osteoporosis
Probiotics • Stimulate the growth of beneficial (“good”) bacteria in the body • Most common probiotic products and use • acidophilus: diarrhea, vaginitis • Activia: constipation • Align: IBS • Culturelle: diarrhea • Flora-Q: IBS • Lactinex: diarrhea, cold sores
Water Deficits • Caused by loss of body fluids resulting from disorders such as • vomiting • diarrhea • edema • large urine output • excessive sweating from fever • acute weight loss
Electrolytes • Compounds that form ions when dissolved in water • Ions are electrically charged particles • sodium and water = blood volume and blood pressure = circulatory collapse
Electrolytes • Na+ - acid-base & water balance, electroactivity • K+ - acid-base & water balance, nervous system function • Ca++- bone formation, coagulation, contractility • Mg++- normal nerve and muscle function
IV Therapy • An isotonic solution has the same level of each type of particles as the body fluids, e.g. 0.9% NaCl
Enteral Nutrition • Patients fed through a tube leading to the GI system (stomach or small intestines) • Preferred method over IV therapy because GI system will remain functional
Parental Nutrition • Parental nutrition (PN): patient fed through a view • Total parenteral nutrition (TPN): provides patient with all nutritional requirements through the parental route
Alternative Supplements • Use of herbs to treat various complaints • Herbs were the original source of many important drugs • Herbs have served as models for many synthetic drugs
Safety Issues • Many people think herbals products are nontoxic and safe, but this is not completely true • FDA prevents relatively poisonous plants from being on the market, however safety issues still exist
Three Particular Safety Concerns • One herb may be mistaken for another • Could result in serious side effects or allergic response • Potential for interactions with other herbs and drugs • Patient may try to treat themselves with herbal products and forgo effective treatment
Some Problems With Herbal Supplements • Lack of regulation and standardization • No FDA quality control • Content of herbal products varies widely • Accurate information is hard to find • Determining toxicity • Some of the most toxic chemicals are obtained from plants
Alternative Supplements • Chamomile- anti-inflammatory, antispasmodic • Chondroitin- arthritis • chromium picolinate- weight loss, improve insulin metabolism • coenzyme Q10- CHF • dong quai- menstrual cramps • Echinacea- common cold • enada, NADH- mental clarity, fatigue
Alternative Supplements • Feverfew- migraine prophylaxis • Garlic- HTN and hyperlipidemia • Ginger- antiemetic • Ginkgo- circulatory stimulant • Ginseng- energy • Glucosamine- arthritis • Hawthorn- cardiovascular problems
Alternative Supplements • Kava- anxiety, psychosis, induces relaxation • Melatonin- sleep • saw palmetto- prostate • St. John’s wort- depression • Valerian- sleep • Yohimbe- impotence
Poisons and Antidotes • Children under 6 at high risk of accidental poisoning • Common drugs that cause the most childhood poisonings • Iron tablets • TCAs • Calcium channel blockers • Opiates • Aspirin • Alcohol
Klor-Con/Potassium Chloride • Used to prevent or to treat low levels of potassium • Category C
Folvite/Folic Acid • B vitamin • Produce & maintain new cells, prevent changes to DNA • Tx: anemia, folic acid deficiency • Preg. Cat A