190 likes | 430 Views
Auritec Pharmaceutics. Privately held Drug Delivery Platform technology Multiple applications Goal is to license 2 nd company founded by TJS. CDS. 1 st company Control Delivery Systems CDS founded 1990 First round financing $34.5 M 1999 Morgan Stanley / Cap Research / T. Rowe Price
E N D
Auritec Pharmaceutics Privately held Drug Delivery Platform technology Multiple applications Goal is to license 2nd company founded by TJS
CDS 1st company Control Delivery Systems CDS founded 1990 First round financing $34.5 M 1999 Morgan Stanley / Cap Research / T. Rowe Price Public- reverse acquisition pSivida Ltd (AUS) Trades NASDAQ (PSDV)
Auritec Founded 2002 Delaware C Offices Santa Monica CA, Boston MA Labs Pasadena CA Multiple academic and industry collaborators
Collaborators Gates Foundation CDC CONRAD USAID IPM Charles River NC State Harvard Caltech Albert Einstein USC U Mass Emory UNC
Plexis Technology Platform Injectable subcutaneous suspension Polymer encapsulation Diffusion based release Small or large molecules IVIVC feasible
IV / IV release - nevirapine In vivo release
Comparison to ALKS Alkermes Particle size ~100u Drug loading <20% Complex mechanism Multiphasic delivery No IVIVC Auritec Particle size ~100u Drug loading > 90% Diffusion based First and pseudo-zero order possible IVIVC feasible
Existing SR injectables Risperdal Consta Leuprorelin Contraception Benzathine and procaine penicillin Zinc Insulins Corticosteroids
SR injectable indications Osteoarthritis Schizophrenia Parkinson’s Diabetic retinopathy Meniere’s HIV transmission Alzheimer’s Depression Malaria TB Diabetes (GLPs) Influenza
Time to Phase I/II 2010 Parkinson’s HIV Transmission Herpes Simplex Diabetic retinopathy Otoprotection Arthritis 2011 Malaria TB Incontinence Graft Rejection
Business Model Bootstrap pSivida, NIH, other granting agencies Fully funded through 2011 License Sell firstborn not self Phase II clinical Non-profit for no profits