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0.00. 0.04. 0.4. 0.00. 0.04. 0.4. 0.00. 0.04. 0.4. 0.00. 0.04. 0.4. 0.00. 0.04. 0.4. A. DAOY wt. 125. 100. 75. c-MYC mRNA expression. % control. 50. c-MYC protein expression. 25. 0. 0.00. 0.04. 0.4. NBT-272 ( µg/ml). DAOY V11. D341. 125. 125. 100. 100. 75. 75.
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0.00 0.04 0.4 0.00 0.04 0.4 0.00 0.04 0.4 0.00 0.04 0.4 0.00 0.04 0.4 A DAOY wt 125 100 75 c-MYC mRNA expression % control 50 c-MYC protein expression 25 0 0.00 0.04 0.4 NBT-272 (µg/ml) DAOY V11 D341 125 125 100 100 75 75 % control % control 50 50 25 25 0 0 0.00 0.04 0.4 0.00 0.04 0.4 NBT-272 (µg/ml) NBT-272 (µg/ml) DAOY M2 D425 125 125 100 100 75 75 % control % control 50 50 25 25 0 0 0.00 0.04 0.4 0.00 0.04 0.4 NBT-272 (µg/ml) NBT-272 (µg/ml) B DAOY wt c-MYC (67 kDa) β-Actin (42 kDa) NBT-272 (µg/ml) DAOY V11 D341 c-MYC (67 kDa) c-MYC (67 kDa) β-Actin (42 kDa) β-Actin (42 kDa) NBT-272 (µg/ml) NBT-272 (µg/ml) DAOY M2 D425 c-MYC (67 kDa) c-MYC (67 kDa) β-Actin (42 kDa) β-Actin (42 kDa) NBT-272 (µg/ml) NBT-272 (µg/ml)