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National Children’s Study University of New Mexico HSC & Valencia County Partnership 3X5X5 Signature Program in Chi

National Children’s Study University of New Mexico HSC & Valencia County Partnership 3X5X5 Signature Program in Child Health –July 15, 2008. Robert D Annett PhD, Principal Investigator Co-Investigators: Sally Davis PhD Renate Savich MD Beth Tigges PhD Kristine Tollestrup PhD

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National Children’s Study University of New Mexico HSC & Valencia County Partnership 3X5X5 Signature Program in Chi

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  1. National Children’s StudyUniversity of New Mexico HSC & Valencia County Partnership3X5X5 Signature Program in Child Health –July 15, 2008 Robert D Annett PhD, Principal Investigator Co-Investigators: Sally Davis PhD Renate Savich MD Beth Tigges PhD Kristine Tollestrup PhD Andy Rowland PhD www.nationalchildrensstudy.gov

  2. What will the NCS Mean to Our Children? • Identification of environmental factors which contribute to health, development and behavior problems • Prematurity, asthma, diabetes, injury, obesity, neurobehavioral development (e.g., ADHD, autism) • Improve understanding of the biology and genetics of health, development, and behavior • Provide evidence-based information on which to base decisions about practice and policy • Economic benefit • 12.5% reduction in obesity/DM  $14.5 billion potential savings • 8% reduction in learning problems  $100 billion potential savings • Provide database for future pediatric research

  3. Overview of Study Procedures • Recruit from pre-conception or early pregnancy • Minimum of 16 home and clinic-based visits (pre-conception through age 21) • Contact by telephone, computerized or mail-in questionnaires up to every 3 months until 5 years of age; annually thereafter

  4. Data Collection: Types of Data • Environmental • air, water, soil, dust, noise levels • samples from child’s environment (home, day care) • Demographic • Psychosocial • Neurodevelopmental • Biological samples from mother, father, child • hair, saliva, urine, blood, breast milk, vaginal swabs • Prenatal • maternal diaries (e.g., nutrition, medications) • ultrasounds • Birth clinical exam data • anthropometrics, blood pressure, dysmorphology, neurologic, dermatologic

  5. Adjunct Studies • Involve a portion of the NCS cohort, utilizing new or existing Study data and Study participants and/or their bio-specimens and/or environmental samples. • Adjunct studies can take place at one or more Study Centers, on all or a portion of their Center participants. • Evaluation criteria: • Scientific merit and significance • Design and methods • Fit, value, and impact on NCS – Benefit to incorporating adjunct studies • Deepen or expand a NCS priority area • Relevance to NCS hypotheses • Proposed study benefits from incorporation into large longitudinal cohort study • NCS investigator must be Co-Investigator • More info: www.nationalchildrensstudy.gov

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