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Water & the Minerals. Fluids. Females 50-55% water Males 55-60% Less water in older adults More in children More in persons who exercise. Fluids. Main functions Shape and structure to cells normal turgor Aids in digestion and absorption of nutrients Transports/ lubricates
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Fluids • Females 50-55% water • Males 55-60% • Less water in older adults • More in children • More in persons who exercise
Fluids • Main functions • Shape and structure to cells • normal turgor • Aids in digestion and absorption of nutrients • Transports/ lubricates • Solvent/ chemical reactions • Stabilizes body temperature
Fluids • Adults metabolize 2.5-3 liters water/day • Excrete 500-600 ml/day to get rid of body wastes • 7-9 liters secreted into GI tract each day • almost all reabsorbed
Fluids • Normal losses 2.5 liters/day • Obligatory • Facultative • Thirst-not always accurate • diminished in elderly • infants can’t tell you • watch color of urine
ECF water outside cell 1/3 body H20 blood plasma interstitial fluids ICF water inside cells 2/3 body H20 site of basic metabolic activity Fluids
Dehydration • Fluid volume deficient or hypovolemia • Output exceeds water intake • Shift of water from ECF to ICF • Lower blood volume • Cellular edema
Dehydration • Hypovolemia symptoms • intense thirst • dry mucous membranes • weak and rapid pulse • orthostatic hypotension • vomiting and confusion • concentrated urine • life threatening -10% weight loss
Signs of dehydration • Headache/ lightheadness • Fatigue • Loss of appetite • Flushed skin • Heat intolerance • Dry mouth and eyes • Dark, scanty urine
Fluid overload • Fluid volume excess or hypervolemia • Fluid intoxication • muscle cramps and low BP • excessive water intake • renal failure or CHF • water shifts from cell to ECF
Fluid overload • Peripheral edema • Rapid, bounding pulse • Distended neck veins • Pulmonary edema/SOB
Fluids • Adequate water intake • 30 ml/kg or 1-1.5 ml/1 kcalorie energy expenditure • Urine should be pale yellow
Minerals • Inorganic elements • Classified as macro and trace elements • by amount • by need
Functions • Structure • Fluid Balance • Vitamin, enzyme, and hormone activity • Nerve cell transmission • Muscle contraction
Acid -Base balance • Determined by pH • Water regulates pH • Normal pH 7.35-7.45 • Acid base buffers • carbonic acid • sodium bicarbonate
Acid -Base Balance • Disturbances • respiratory acidosis • chronic lung disease • metabolic acidosis • ketosis • respiratory alkalosis • hyperventalating • metabolic alkalosis • vomiting
Mineral salts • NaCl in body water • Movement directed by cells • Water follows salt • Separate into ions in solution • Conduct electricity • Called electrolytes
Electrolytes • Cations-NA+, K+ • Anions-Cl- • Usually balanced
Sodium • Principle electrolyte in ECF • Primary regulator ECF volume • Maintains acid base balance • Muscular irritability • Nerve impulse transmission • Intestinal secretions • 35-40% skeleton
Sodium • 1 gram sodium in 1/5 t. of NaCl • Salt is 39% sodium • Use less with HTN, CHF, and Kidney Failure • Adjust depending on climate and physical activity • Suggested intake 2400 mg or 1000mg/1000 kcalories
Sodium • Increased losses with vomiting and diarrhea • Replace both Na+ and water
Potassium • Principle cation in ICF • Maintains cell integrity • Keeps heart beat steady • Deaths from severe diarrhea or dieresis • Assists in CHO and protein metabolism
Potassium • High K foods associated with decreased risk of stroke and lower blood pressure • Hypokalemia • too low=death • Hyperkalemia • too high =death
Lower Sodium Diet • Reduce sodium gradually • Learn to read the food labels and compare brands • Fresh is best • Balance high and low sodium foods • Experiment with herbs,etc.
Chloride • Principle anion of ECF • Not usually treated separately from sodium problems
Calcium • Most abundant • 99% bone and teeth • 1% serum • Bound with P04-3 and Mg++
Calcium • Bones replete serum • Serum Ca++ • bone and teeth formation • controls muscle contractions • transmits nerve impulses • blood clotting • secretion of hormones
Calcium • Calcium • Regulated very tightly • 30-40% dietary calcium absorbed • bound to oxalates & phytates in plant foods • New recommendations
Calcium • Serum levels kept constant • Vitamin D and parathyroid hormone raises Ca++ levels PRN • Calcium travels with Albumin in blood-need to do corrected Ca++ calculation if Albumin low
Calcium Deficiencies • Means less bone density • Osteoporosis- thin, white or Asian women most at risk • Rickets- malabsorption of Ca++
Calcium Deficiencies • Sedentary lifestyle • less absorption • Low calcium diet • increased blood pressure • ETOH and smoking increases losses
Calcium Supplements • Carbonate • Citrate • Acetate • NO oyster shell
Supplements • No more than 2500mg per day • Count amounts from food • Smaller divided doses • Do not take iron and calcium at the same time • Plenty of fluids
Calcium Excesses • Constipation • Kidney Stones
Calcium Sources • Milk • Cheese • Yogurt • Soy & other legumes • Whole grains • Green Leafy Vegetables
Phosphorous • Combined with Ca++ in bone and teeth • 85% in bones • Major body buffer • Important in energy transfers-ATP
Phosphorous • Absorption regulated by parathyroid hormone • Excesses excreted in urine • Renal insufficiency = high serum levels
Phosphorous Deficiencies • Malnutrition • ETOH abuse • Starvation
Phosphorous Sources • Meats • Poultry • Fish • Eggs • Legumes • Milk and Dairy Products • Soft drinks
Magnesium • Small amount in body • Critical to operation of hundreds of enzymes • Smooth muscle relaxation • Necessary for release of energy • Holds calcium in tooth enamel
Magnesium Deficiency • Vomiting and diarrhea • ETOH abuse • Protein malnutrition • Causes hallucinations in ETOH withdrawal • Prolonged muscle contractions
Magnesium Sources • Green leafy vegetables • Nuts • Legumes • Whole grains • Seafood
Iron • 3-5 g stored in body • 2/3 as heme in hemoglobin • 1/3 as ferritin • RBC carries O2 to tissues • Needed for new cells
Iron • 10-15% dietary iron absorbed • Amount increases in deficiency • Nonheme Fe+++ ferric • plant source • Nonheme and heme Fe++ ferrous • animal source
Iron Toxicity • Repeated transfusions • Polycystic disease • Iron poisoning • Symptoms • N&V • shock • convulsions and coma
Iron Deficiencies • Most deficient nutrient in US • Nutritional Anemias • Hemorrhagic Anemias • Postgastrectomy anemia • Malabsorption anemia • Chronic disease anemia
Iron Deficiencies • Symptoms • weakness and fatigue • headaches • apathy • Pica-eating of non-nutrient substances • ice, clay, paste, starch, kaolin
Iron Deficiency Anemia • Increase food sources • Include iron fortified cereals • Know heme iron sources • Add sources of Vitamin C • Drink coffee & tea between meals, not with meals • Cook in iron pots
Iron Sources • Liver • Lean meat • Dried beans • Fortified cereals