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Diabetic Control and Smoking. - Christopher Laylan Student, UW-Madison Madison, WI - Rodney Erickson, MD Mayo Clinic Health System-Tomah Tomah, WI -Richard Erickson, MS Texas Tech University Lubbock, TX. Introduction.
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Diabetic Control and Smoking - Christopher Laylan Student, UW-Madison Madison, WI - Rodney Erickson, MD Mayo Clinic Health System-Tomah Tomah, WI -Richard Erickson, MS Texas Tech University Lubbock, TX
Introduction • Tobacco use and diabetes are risk factors for the development and progression of atherosclerotic vascular disease and the associated increase in morbidity and mortality • Diabetes on the increase • Expected to raise 165% by 2050 (6) • Smoking is on the decline…right? • Yes, among the general population • No, among age group 18-24 (8) • Smoking at this age leads to more smoking in future (8) • However, smoking at this age is partly due to “social smoking”
Earlier Studies • Smoking accelerates onset of diabetes mellitus (1) • meta-analysis in 2007 reported that smokers had a 1.4 higher relative risk of developing diabetes compared to nonsmokers. • 1995 European study found smokers had higher average glycosolatedhemoglobins (A1C) than non-smokers for those with Type 1 diabetes. • No reports of the effect of tobacco use on glycemic control among those diagnosed with Type II diabetes
Our study • Our study looks at the relationship between tobacco use and glycemic control among patients with diabetes, type 1 and 2. • Do diabetics who smoke have worse glycemic control?
Why?? • Physiological • Smoking raises blood glucose (7) • Socio-Economical Position (SEP) • People of lower SEP more likely to smoke (3) • Less exercise (5) • Poor eating habits due to decreased knowledge (6) • Less health care
Methods • Accessed diabetic patient records from 5 clinics in Wisconsin • Total of 1,963 charts • Observed 4 tests for determining diabetic control of smokers and non-smokers • Hba1c (main test we observed) • Blood Pressure • LDL • Aspirin use
Methods (Cont’d) • Test standards • Hba1c greater than or equal to 8% • BP < 140 / 90 mmHGg • LDL < 100 dL • Aspirin use = yes or no
Results • Hba1c Results • non-smokers: mean of 7.27% • Total of 1,606 • smokers: mean of 7.56% • Total of 349 • BP Results • Non-Smoker • High = 357 (22.5%) • Low = 1,231 (77.5%) • Smoker • High = 111 (31.8%) • Low = 238 (68.2%)
Results (cont’d) • LDL Results • Total of 1,866 • Non-Smokers • High = 264 (17.2%) • Low = 1,268 (82.8%) • Smokers • High = 105 (32.5%) • Low = 218 (67.5%) • Aspirin Result • Total of 1,890 • Non-Smokers • no = 67 (4.3%) • yes = 1,485 (95.7%) • Smokers • No = 19 (5.6%) • Yes = 318 (94.4%)
Conclusion • This study shows that diabetic nicotine users are 1.4 times more likely to have Hba1c values greater than the goal of 8% compared to diabetic non-nicotine users. • This study needs to confirmed on larger number of clinics
Bibliography • (1) Will, JC. (2000, September 05). Cigarette smoking and diabetes mellitus; evidence of a positive association from a large prospective cohort study. Retrieved from http://ije.oxfordjournals.org/content/30/3/540.full.pdf+html • (2) Power, C. (2004, October 28). The contribution of childhood and adult socioeconomic position to adult obesity and smoking behaviour: an international comparison. Retrieved from http://ije.oxfordjournals.org/content/34/2/335.short • (3) Lantz, PM, PhD. (1998, June 03).Socioeconomic factors, health behaviors, and mortality results from a nationally representative prospective study of us adults. Retrieved from http://jama.ama-assn.org/content/279/21/1703.full.pdf+html • (4) Boule, MG, MA. (2001, September 12).Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus. Retrieved from http://jama.ama-assn.org/content/286/10/1218.short • (5) Conway, TL, Ph.D. (1992, November).Smoking, exercise, and physical fitness. Retrieved from http://www.sciencedirect.com/science/article/pii/009174359290079W • (6) Boyle, JP, PhD. (2001, November).Projection of diabetes burden through 2050 impact of changing demography and disease prevalence in the u.s.. Retrieved from http://care.diabetesjournals.org/content/24/11/1936.short • (7) Wechsler, H, PhD. (1998, November 18).Increased levels of cigarette use among college students a cause for national concern. Retrieved from http://jama.ama-assn.org/content/280/19/1673.full.pdf+html • (8) Moran, S, MD, MSCE. (2004, October 01).Social smoking among us college students . Retrieved from http://pediatrics.aappublications.org/content/114/4/1028.full • (9) Wikstrom, K. (2010, November 18). Socio-economic differences in dysglycemia and lifestyle-related risk factors in the finnish middle-aged population. Retrieved from http://eurpub.oxfordjournals.org/content/early/2010/11/18/eurpub.ckq164.abstract • (10) Smith, BT. (2011, January 17). Life-course socioeconomic position and type 2 diabetes mellitus the framingham offspring study. Retrieved from http://aje.oxfordjournals.org/content/173/4/438.abstract • (11) Zhang, L, MD. (2011, February 25).Association between passive and active smoking and incident type 2 diabetes in women. Retrieved from http://care.diabetesjournals.org/content/34/4/892.abstract