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Chapter 41. Digestive System. Digestion and absorption. It is the physical and chemical break down of food Absorption It is the passing of the digested food through the epithelial cells into the blood stream. Digestive system. Gastrointestinal tract. It is the alimentary canal Mouth
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Chapter 41 Digestive System
Digestion and absorption • It is the physical and chemical break down of food • Absorption • It is the passing of the digested food through the epithelial cells into the blood stream
Gastrointestinal tract • It is the alimentary canal • Mouth • Pharynx • Esophagus • Stomach • Small intestine • Large instestine
Accessory digestive organs • Salivary glands • Gallbladder • Liver • Pancreas • Teeth
General histology of the gastrointestinal tract • It has 4 tunics • Mucosa • Epithelium – simple columnar • Lamina propria – areolar tissue • Muscularis mucosa • Smooth muscle that enables movement of the mucosa
General histology of the gastrointestinal tract • Functions of the mucosa are secretion, absorption, protection • Submucosa • Dense connective tissue • Blood vessels • Lymph nodes and vessels • Submucosal plexus • Functions are nutrition and protection of the mucosa
General histology of the gastrointestinal tract • Muscularis externa • Inner circular layer of smooth muscle • Outer longitudinal layer of smooth muscle • Myenteric plexus • Allows GI movements
General histology of the gastrointestinal tract • Serosa (abdominal organs) • Most outer layer • Mesothelium – areolar tissue • Functions is to reduce friction between GI organs • Adventitia • Coarse fibrous tissue that binds the GI organs to the surrounding tissues. Anchors and protects them
Macroscopy of the digestive tract • Oral cavity or mouth • Oral cavity • Lips or labia • Superior and inferior labial frenulum • Cheeks • Palate • Soft with uvula • Hard • Palatine raphe
Macroscopy of the digestive tract • Tongue • Mylohyoid muscle • Lingual frenulum • Vestible • Palatine tonsil • Palatoglossal arch • Palatopharyngeal arch
Macroscopy of the digestive tract • Lingual tonsil • Salivary glands • Saliva • Salivary amylase • Pharynx • Nasopharynx • Oropharynx • Laryngopharynx
Macroscopy of the digestive tract • Esophagus • Peristalsis • Gastroesophageal sphincter • Adventitia and not serosa • Stomach • Cardiac region • Fundus • Body
Macroscopy of the digestive tract • Pyloric region • Pyloric sphincter • Greater curvature • Greater omentum • From the greater curvature down to the abdominal organs • Lesser curvature
Macroscopy of the digestive tract • Lesser omentum • From the lesser curvature to the liver • Gastric pit • Gastric rugae • Function of the stomach is to process the food forming the chyme
Histology of the stomach • Mucosa • Gastric glands • Chief or zymogenic cells: • Located on the fundus • Produce pepsinogen
Histology of the stomach • Parietal cells: • Located on the fundus • Produce HCL • Produce intrinsic factor Enteroendocrinecells: • Located on the pyloric region • Release hormones • Submucosa
Histology of the stomach • Muscularis externa • Oblique layer • Circular layer • Longitudinal layer • Gastroesphageal junction (Cardioesophageal) • Stratified squamous epithelium on the esophagus • Simple columnar on the stomach
Small intestine • From the pyloric sphincter to the ileocecal valve • Mesentery Proper • Double layer of peritoneum that attaches the small intestine to the posterior body wall
Small intestine • Plicae • Deep folds of the mucosa and submucosa • They cause the chyme to spiral through the intestine slowing and mixing it • Intestinal crypts of crypts of Lieberkuhn • It is the invaginated area of the mucosa between the villi
Small intestine • Lacteal • It is the lymphatic capillary present in each villus • Function of the small intestine • Nutrients absorption
Small intestine • Duodenum • Pancreatic duct • Bile duct • Hepatopancreatic ampulla • Major duodenal papilla • Hepatopancreatic sphincter or sphincter of Oddi • Duodenal glands or Brunner’s glands – located in the submucosal layer
Small intestine • Jejunum • Where the food is most absorbed • Ileum • Ileocecal valve • Peyer’s patches • Aggregation of lymphoid tissue more prominent in the ileum
Small intestine • Superficial structures of the small intestine that increases the absorptive area of the mucosa • Villi • Fingerlike projections of the mucosa
Small intestine • Microvilli or brush border • Projections of the cell membrane of the columnar epithelium • Brush border enzymes • Plicae
Histology of the small intestine • Identify these structures on the slide: • Plica • Cripts • Villi • Brush border • Layers of the intestine
Histology of the small intestine • Duodenum • Submucosa with Brunner’s glands • Jejunum • Longest, leafy villi • Ileum • Submucosa with Peyer’s patches
Large intestine • From the ileocecal valve to the anus • Mesocolon • Attaches the large intestine to the body wall • Cecum • It is the first part • Appendix • A blind tube like structure connected to the cecum
Large intestine • Colon: • Ascending • Right side of the abdominal cavity • Right colic (hepatic) flexure • It is retroperitoneal • Transverse • Cross the abdominal cavity • Left colic (splenic) flexure
Large intestine • Descending • It is retroperitoneal • Sigmoid • S-shaped • Located in the pelvis • Rectum
Large intestine • Anus • External sphincter - skeletal muscle • Voluntary • Internal sphincter – smooth muscle • involuntary
Large intestine - structures • Tenia coli • It is the longitudinal muscle layer of muscularis externa • It is in the shape of a muscle band • Haustra • Pocket like sacs of the large intestine • It is caused by the tenia coli
Large intestine - structures • Epiploic appendages • Fat-filled pouches of visceral peritoneum hanging for the colon’s surface
Large intestine • Functions of the large intestine • Consolidate and propel the fecal matter to the anus • Site for intestinal bacteria to synthesize vitamins B and K • Site for water absorption
Histology of the large intestine • Lumen • Crypts • Layers of the digestive tract • Mucosa with the maximum amount of goblet cells • No villi
Accessory digestive organs • Teeth: • Deciduous (milk teeth) • They appear between 6 month and 2 ½ years of age • They begin to shed at 6 years of age • They are completely shed by the age of 12
Accessory digestive organs • Permanent • They begin to appear at 6 years of age • They last for a lifetime
Accessory digestive organs • Classification of the teeth • Incisors • Chisel shaped • Shearing action when biting • 4 superiors and 4 inferiors (2 centrals and 2 laterals) • Single-rooted
Accessory digestive organs • Canines • Cone-shaped • It tears the food • 2 superiors and 2 inferiors • Single-rooted
Accessory digestive organs • Premolars • Two cusps • It grinds the food • 4 superiors and 4 inferiors • 2 first premolars • 2 second premolars • Generally single-rooted • 1st premolar may have 2 roots
Accessory digestive organs • Molars • They have broad crowns • Rounded cusps • 6 superiors and 6 inferiors • 2 first molars • 2 second molars • 2 third molars or wisdom teeth • They have 2 roots • They grind food into fine pieces
Accessory digestive organs • Dental formula: • Deciduous • 2,1,0,2 2,1,0,2 • Permanent • 2,1,2,3 2,1,2,3
Accessory digestive organs • Anatomy of the teeth • Crown • Clinical • Anatomical • Enamel • It consists mainly of calcium salts • Gum or gingival • Gingival sulcus and margin
Accessory digestive organs • Neck • Root • Cementum • Periodontal ligament • Dentin • Pulp • Contain blood vessels and nerves • Pulp cavity