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SMART PROTOCOLS Self Describing Executable Elements. Laboratory protocols, comprising hundreds of individual steps Protocols are written in natural language; they are often presented in a “recipe” style. Olga Giraldo ogiraldo@delicias.dia.fi.upm.es Ontology engineering group (OEG)
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SMART PROTOCOLS Self Describing Executable Elements • Laboratory protocols, comprising hundreds of individual steps • Protocols are written in natural language; they are often presented in a “recipe” style Olga Giraldo ogiraldo@delicias.dia.fi.upm.es Ontology engineering group (OEG) Universidad Politécnica de Madrid
Laboratory Protocols Supporting the Results How can we formally represent laboratory protocols?
FormalizingLaboratoryProtocols nanopublication has assertion has provenance Protocol provenance “Incubatethecentrifugetubes at 65°C in a waterbathfor 10 min.” • Incubatethecentrifugetubes at 65°C in a waterbathfor 10 min. • Rinse DNA briefly in 1-2 ml of wash. • Incubate at -20C overnight. has supporting has attribution hasUnitofMeasure hasAction hasUnitofMeasure hasObject indicate different length of time 2 seconds?, 5-10 seconds?... supporting attribution hasObject 10 min. exact:incubate 65°C Authors, dates Protocol where it is used … others smart:centrifugetubes obi:waterbath
In a Nutshell Humans Nanopublications in the form of actions to be executed Executable Instructions Lab. protocols WoD Machines Lab Robots • Structural Elements • Tittle, authors, sections, PROV, etc Self-Describing • Domain Knowledge • Domain Ontologies
Acknowledgments Special Thanks to Oscar Corcho and Alexander Garcia Also, to Leyla Garcia Thanks to my OEG and the Wf4Ever project