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Psychosocial Genomics and Interpersonal Neurobiology – a meeting of mind and body

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Psychosocial Genomics and Interpersonal Neurobiology – a meeting of mind and body

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  1. Angaben über Beziehungen zur IndustrieAngaben über Beziehungen zur IndustrieIch erkläre hiermit, dass ich keine geschäftliche, persönliche und materielle Beziehungen zu Industrieunternehmen unterhalten habe oder gegenwärtig unterhalte, welche bezüglich zu dem von mir hier vorgetragenen Thema relevant sind. Disclosure InformationI hereby declare that I had or have had no business or personal interests in industrial enterprises which are relevant for the topic of my speech.

  2. Psychosocial Genomics and Interpersonal Neurobiology – a meeting of mind and body Richard Hill Australia

  3. Psychosocial Genomics Ernest Rossi, PhD The deep psychobiological processes of “activity or experience-dependent gene expression and brain plasticity” associated with creativity and psychotherapy

  4. Interpersonal Neurobiology Dr Daniel Siegel An interdisciplinary approach to engage in a deeper understanding of the complex neurobiological processes of self and interpersonal integration that lead to a state of mental and biological wellbeing.

  5. A wonderful worm! Caenorhabditis elegans

  6. Psychosocial Genomics • Activity dependent gene expression • Activity dependent epigenetic expression • Silencing directly – DNA methylation • Silencing structurally – histone acetylation & nucleosome/chromatin tension

  7. Therapeutic Brain Plasticity

  8. Interpersonal Neurobiology

  9. Disturbance, Disruption, and Interference to Integration

  10. Certainty (predictability) Complexity Harmony (Edge of Rigidity) R I G I D I T Y Edge of Chaos Uncertainty (unstable and fragile) CHAOS

  11. Self Organising System • Adaptation • Dis-integration • Hierarchy of needs • Habituation • Automation / normalisation Optimal • Immune system • Associative brain • Positive emotions • Seeking • Social brain

  12. IPNB Integrative processes 8 Domains of Integration • Conscious • Horizontal • Vertical • Memory Narrative State Temporal Interpersonal

  13. Mind to Body Integration • Gene expression – epigenetic processes • Biochemical conversation between the brain and the endocrine system – via macrophages • Inflammatory biochemistry – IL 1,2,6, TNFa

  14. A Pilot Study of Positive Expectations and Focused Attention via a New Protocol for Optimizing Therapeutic Hypnosis and Psychotherapy Assessed with DNA Microarrays: The Creative Psychosocial Genomic Healing Experience Rossi,Iannotti, Cozzolino, Castiglione, Cicatelli, Rossi The International Journal of Sleep, Dreams and Hypnosis Vol 10, No.2, 2008

  15. relative / Chronic disease is a maladaptive balance

  16. The Inflammatory SystemThe Secret Link • Responds to Trouble • Too much – too little • React – shut down • Make known Mood - PAIN - Sleep modernity

  17. What we doHow often we do itOur state of mind when we do it determinesour construction The Life We Live and How We Live It is fundamental

  18. The Purpose of Life To creatively participate in the experience

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