1 / 6

Side effects of anti-TB medications HREZ

Side effects of anti-TB medications HREZ. Isoniazid. Isoniazid -induced hepatitis-most common major toxic effect Peripheral neuropathy CNS toxicity-memory loss, psychosis,seizures Fever and skin rashes Drug-induced SLE Hematologic abnormalities Provocation of pyridoxine deficiency anemia

nuri
Download Presentation

Side effects of anti-TB medications HREZ

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Side effects of anti-TB medications HREZ

  2. Isoniazid • Isoniazid-induced hepatitis-most common major toxic effect • Peripheral neuropathy • CNS toxicity-memory loss, psychosis,seizures • Fever and skin rashes • Drug-induced SLE • Hematologic abnormalities • Provocation of pyridoxine deficiency anemia • Tinnitus • Gastrointestinal discomfort Katzung, B, Basic and Clinical Pharmacology 10th ed., McGraw Hill 2007, page 773

  3. Rifampicin • Orange urine, sweat and tears • Rashes • Thrombocytopenia • Nephritis • Light-chain proteinuria • Flu-like sydrome(fever, chills, myalgia, anemia and thrombocytopenia) Katzung, B, Basic and Clinical Pharmacology 10th ed., McGraw Hill 2007, page 774

  4. Ethambutol • Retrobulbar neuritis • most common serious adverse event • Loss of visual acuity and red-green color blindness • Hypersensitivity syndrome consisting of cutaneous reaction (such as rash or exfoliative dermatitis) • Fever and lymphadenopathy Katzung, B, Basic and Clinical Pharmacology 10th ed., McGraw Hill 2007, page 774 http://www.drugs.com/sfx/ethambutol-side-effects.html

  5. Pyrazinamide • Hepatotoxicity-major adverse effect • Nausea • Vomiting • Fever • hyperuricemia Katzung, B, Basic and Clinical Pharmacology 10th ed., McGraw Hill 2007, page 775

  6. *Streptomycin • Vertigo and hearing loss • nausea, vomiting • paresthesia of face • rash • fever • Urticaria • angioneuroticedema • eosinophilia Katzung, B, Basic and Clinical Pharmacology 10th ed., McGraw Hill 2007, page 775 http://www.drugs.com/sfx/streptomycin-side-effects.html

More Related