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Cornwall Health Library: Katy Oak Catriona Organ

An activity-based journal club to help staff & students improve confidence at reading scientific papers. Cornwall Health Library: Katy Oak Catriona Organ. Workshop: Background Activity More ideas.

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Cornwall Health Library: Katy Oak Catriona Organ

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  1. An activity-based journal club to help staff & students improve confidence at reading scientific papers Cornwall Health Library: Katy Oak Catriona Organ

  2. Workshop: • Background • Activity • More ideas

  3. Knegt, N.C. et al Behavioral pain indicators in people with intellectual disabilities: a systematic review. Journal of Pain 14 (9) p885-896

  4. West, R. Placebo-controlled trial of Cytisine for smoking cessation. NEJM 2011 365 (13) p. 1193-1200

  5. Journal Club objectives: • Increase understanding & confidence reading articles • Improve writing assignments • Better analysis of academic articles

  6. Journal Club format: • Activity • Checklist • Paper

  7. Agree Strongly Agree

  8. "A journey of a thousand miles begins with a single step“Lao Tzu Reading RCT papers

  9. Does caffeine increase the heart rate of people attending the HLG Conference in Keele?

  10. Sample Randomisation Control group Experimental group Measure heart rate Measure heart rate placebo caffeine

  11. From here: Slides for explanation if needed

  12. Power Calculation • Before trial • Sample size • Ability to detect smallest clinically relevant difference • 0.8 or 80% probability of finding a difference if it exists

  13. West, R. Placebo-controlled trial of Cytisine for smoking cessation. NEJM 2011 365 (13) p. 1193-1200

  14. Randomisation 01, 10, 02, 34, 75, 36, 09, 24, 98 O, E, E, E, O, E, O, E, E Odd = placebo Even = experimental

  15. Randomisation 01, 10, 02, 34, 75, 36, 09, 24, 98 O, E, E, E, O, E, O, E, E Odd = placebo Even = experimental

  16. P - values The probability that the result would have occurred by chance. The lower the p – value, the less likely that the result is due to chance. P < 0.05 statistically significant. P < 0.01 = 1 / 100 P < 0.001 = 1/ 1000

  17. Confidence Intervals We are 95% confident that the true population result lies within the given range

  18. Confidence Intervals Difference between MEANS If the range crosses zero then the result is not significant Difference between RISK & ODDs If the range crosses 1 then the result is not significant

  19. How good is the methodology? How far can the results be …...generalised to a wider population?

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