1 / 7

Preliminary results of prophylactic intracameral moxifloxacin 0.5% ophthalmic solution in cataract surgery patients

Preliminary results of prophylactic intracameral moxifloxacin 0.5% ophthalmic solution in cataract surgery patients. Osman Sevki Arslan 1 , Mustafa Ilker Toker 2 , Akif Ozdamar 1 , Nihat Polat 1 , Ceyhun Arici 1

ohio
Download Presentation

Preliminary results of prophylactic intracameral moxifloxacin 0.5% ophthalmic solution in cataract surgery patients

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Preliminary results of prophylactic intracameral moxifloxacin 0.5% ophthalmic solution in cataract surgery patients Osman Sevki Arslan1, Mustafa Ilker Toker2, Akif Ozdamar1, Nihat Polat1, Ceyhun Arici1 1Istanbul University Cerrahpasa Medical School, Department of Ophthalmology, Istanbul, TURKEY, 34098 2Cumhuriyet University, School of Medicine, Department of Ophthalmology, Sivas, TURKEY There were no financial interest of any authers

  2. PURPOSE: • To determine the efficacy of prophylactic intracameral moxifloxacin 0.5% ophthalmic solution (Vigamox) in patients having cataract surgery.

  3. METHODS: • Preoperatively, patients received 1 drop of topical Vigamox every 15 minutes at least 4 times. • 0.1 mL intracameral moxifloxacin 0.5% ophthalmic solution containing 500 mg of moxifloxacin was given to the all eyes as the last step of phacoemulsification.

  4. METHODS: • Postoperative antibiotics included topical Vigamox every 2 hours while awake on the day of the surgery. The Vigamox was reduced to 4 times a day until the bottle was empty. • Preoperative and 1-month postoperative anterior chamber reaction, corneal endothelial cell density, corneal thickness, and ocular infections were observed in 36 eyes that had cataract surgery with intracameral moxifloxacin.

  5. RESULTS: • All 30 eyes of 29 patients completed the study. The mean age was 52.2 years ± 20.9 (SD) (range 19 to 83 years). The mean follow-up time was 1.63 months ± 0.34 (range 1 to 2 months). All eyes had a postoperative best corrected visual acuity of 20/30 or better. • All eyes had trace to +2 cells and flare anterior chamber reaction only on the first day after surgery.

  6. RESULTS: • The mean endothelial cell count was 2347.12 cells/mm2 preoperatively and 2281.67 cells/mm2 postoperatively. The mean difference was 70 cells/mm2, which not statistically significant (P>0.05). • The increase of 14.97 µm in postoperative pachymetry 1 month after surgery was not statistically significant (P> 0.05). There were no infections in any cases.

  7. CONCLUSION: • Although this patients group is small and there is a need to wide and long term studies, with our preliminary results, we can say intracameral Vigamox 0.5 mg/mL was effective and safe to prevent from the postoperative infections.

More Related