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Topic 4.2 & 10.1 Notes. Meiosis. A reduction in chromosomes to form HAPLOID cells. 2N to 1N. Homologous pairs . They associate with each other during prophase 1 through synapsis. Chromosomes replicate in which phase?. S phase!. Prophase 1.
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Meiosis • A reduction in chromosomes to form HAPLOID cells. • 2N to 1N
Homologous pairs • They associate with each other during prophase 1 through synapsis.
Chromosomes replicate in which phase? • S phase!
Prophase 1 • The homologous chromosomes form BIVALENTS. These are replicated homologous chromosomes. • The sister chromatids are next to each other, joined at the centromere.
Crossing Over • Non sister chromatids may cross over during prophase 1 leading to recombinant alleles.
More detail on Prophase 1 Synapsis-the chromosomes associate Crossing Over-The Chiasma are the points at which they cross over. A Holliday junction forms when they anneal. This increases genetic diversity!
Metaphase 1 • Bivalents line up at the equator double file. • There are many positions that they can align themselves in. • This adds to the genetic variation…more on this later!
Anaphase 1 • This is where the reduction takes place. The pairs separate, but the sister chromatids remain attached!
Telophase 1 • The cells are no longer diploid here. • The chromosomes may not be exact matches of each other due to crossing over.
Prophase II • The nuclei break down again, but the chromosomes do not cross over again.
Metaphase II • Random orientation again contributes to variation in gametes.
Anaphase II • Chromatids are pulled to the opposite poles.
Mendel and Independent Assortment • The presence of an allele of one of the genes in a gamete has no influence over which allele of another gene is present. • This is only true for unlinked genes. • Click here for a more detailed explanation.
HOMEWORK 4.2/10.1 • Make a T Chart to compare/contrast mitosis and meiosis. • Please include as many as possible, but a minimum of 6. • You may need to do some research ON YOUR OWN. • Due Friday