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Primary HIV-Associated Neurologic Problems

Primary HIV-Associated Neurologic Problems. HIV-associated neurocognitive disorder and dementia Peripheral neuropathy Myelopathy Myopathy. Neurocognitive Impairment in the Pre-Antiretroviral, Pre-HAART, and HAART Eras. Grant 1987 HNRC-500 1995 CHARTER 2008. 87%. 56%. 54%. 54%.

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Primary HIV-Associated Neurologic Problems

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  1. Primary HIV-AssociatedNeurologic Problems • HIV-associated neurocognitive disorder and dementia • Peripheral neuropathy • Myelopathy • Myopathy

  2. Neurocognitive Impairment in the Pre-Antiretroviral, Pre-HAART, and HAART Eras Grant 1987 HNRC-500 1995 CHARTER 2008 87% 56% 54% 54% Patients With Neurologic Impairment (%) 52% 44% 44% 43% 31% 17% 9% 0% HIV Negative CDC-A CDC-B CDC-C HIV Positive

  3. HIV Neuropathogenesis:Post HAART Jones G, et al. Neurobiol Dis. 2006;21:1-17.

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