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Figure 2. - + - - - + - -. Epsin 1 siRNA. - - + - - - + -. Eps 15 siRNA. whole cells. lysosomes. ErbB2. LAMP2. - + - +. PS341 (10nM). A. B. Control. D. PS341 (10nM, 24h). ErbB2. actin.
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Figure 2 - + - - - + - - Epsin 1 siRNA - - + - - - + - Eps 15 siRNA whole cells lysosomes ErbB2 LAMP2 - + - + PS341 (10nM) A. B. Control D. PS341 (10nM, 24h) ErbB2 actin - + - + PS341 (50nM) - - + + ErbB2 LAMP2b DAPI + merge Cyclohex C. control PS341 (20nM, 24h) ErbB2 ErbB2 Actin - - - + - - - + CHC siRNA PS341 Control Epsin Control Control CHC siRNA: CHC Epsin1 actin actin Cyclohex Cyclohex + PS341