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Multiple Scleroses: The Neuroscientific Paradigm. Amna Hyder, Hannah Dies, Yohan Yee, Piotr Roztocki † † Honours Integrated Science, McMaster University. Context. Multiple Sclerosis. Types of Neurons. Structure of a T ypical Neuron. Acton Potential. Action Potential. Electrodiffusion.
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Multiple Scleroses: The Neuroscientific Paradigm Amna Hyder, Hannah Dies, Yohan Yee, Piotr Roztocki† †Honours Integrated Science, McMaster University
Capacitance • C = (Charge) / (Voltage) = Q/V • HIGH capacitance: • More ions are required to charge the membrane • Reduces the distance at which the current propagates • Want LOWER capacitance!
Blood brain barrier break down • biomarkers • T-cell attack • molecular mimicry • virus cause?
Treatment Common: • Corticosteroids • Interferon-β Emerging Treatments: • Remyelination • CCSVI Surgery
Epidemiology Evidence for: • Infection-related Factors • Genetic Factors • Environmental Factors