Amino Acid Structure

2. Alanine Amino Acid Structure From DNA a strand of mRNA is transcribed. This mRNA is read by a ribosome in the cytoplasm which in turn constructs the appropriate protein sequence with the help of specific tRNA’s. What is the protein constructed of? _________________ Amino Acids How many amino Acids are there? _______ 20 Today your going to take a look at the structure and properties of each of the twenty amino acids. Go to the following link to complete the assignment below. LINK:http://wiki.cmbi.ru.nl/index.php/Amino_acid In your notes: Provide a basic description of an amino acid (be sure to describe the general structure and the specifics of the peptide bond involved) List all twenty of the Amino Acids, give a description of their properties and draw a line figure of it’s chemical composition in your notes Questions: In your notes draw the resulting structure from a dehydration RxN between Glycine and Serine Now the resulting structure from a dehydration RxN between Aspartic Acid and Asparagine

3. Amino Acid Investigation Continued…. Use the two following web sites to help you better see amino acid structure and the process of a dehydration reaction http://www.biotopics.co.uk/JmolApplet/aminoacidcategories110.html http://www.biotopics.co.uk/as/aminocon.html http://www.biomed.curtin.edu.au/biochem/tutorials/AAs/AA.html In your notes: List all twenty of the Amino Acids, give a description of their properties and draw a line figure of it’s chemical composition in your notes Provide a basic description of an amino acid (be sure to describe the general structure and the specifics of the peptide bond involved) Questions: In your notes draw the resulting structure from a dehydration RxN between Glycine and Serine Now the resulting structure from a dehydration RxN between Aspartic Acid and Asparagine Now include in your notes the label given to each based on it’s R group characteristics

4. Translation The process by which messenger RNA directs the amino acid sequence of a growing polypeptide during protein synthesis http://www.dnai.org/a/index.html • Click on “code” • then on “reading the code” • Then visit each of the sections listed below and answer each of the questions provided for the given sections. Problem • Pieces of the puzzle • The other Codons • Defining the gene • Putting it together • Translation • Interactive

5. Protein Synthesis • Up to this point we have discussed: • DNA and the transcription of DNA into a resulting mRNA strand. • We have also covered Translation which is the synthesis of a protein from the instructions of mRNA. This synthesis is completed by the ribosome with the help of tRNA’s which bring the appropriate amino acid to the ribosome to be added to the protein being created. • We have covered amino acid structure and the dehydration reaction which occurs allowing each amino acid to be added to the protein being synthesized • We have also started to look at mutations… • today we will continue to look at different mutations and their effect on the completed protein structure http://highered.mcgraw-hill.com/sites/0072552980/student_view0/chapter9/animation_quiz_5.html

6. 2-5b Genetic Disorders Go to the web site below and answer the questions provided. Your Genes Your Health http://www.ygyh.org/index.htm There are 15 genetic disorders listed on this web site. For each of the disorders get a brief overview of the disorder from the “what is it page” and then in your notes indicate the following for each of them: What causes it, How is it inherited and How is it treated.

7. Disorder Additions The following three are not available on the ygyh web site Please go to www.aarp.org Click on Health Under tools, click on “View all health tools” Scroll down and click on “Health Encyclopedia” As you have done for the others: in your notes indicate the following for each of them: What causes it, How is it inherited and How is it treated. Disorders: Turner Syndrome Friedreich’s Ataxia