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.L-kynurenine (Kyn) is a naturally occurring ligand for the Aryl hydrocarbon receptor (AhR), recognized for its diverse biological effects. This study sheds light on the interactions and implications of Kyn as an endogenous ligand, offering insights into its potential therapeutic applications. The findings from Bessede et al. published in Nature (2014) provide a comprehensive understanding of Kyn's regulatory functions within the body.
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L-kynurenine (Kyn) is an endogenous AhR ligand. A Bessede et al. Nature 000, 1-7 (2014) doi:10.1038/nature13323