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Peri-anal disease and IBD in Adolescence. Bruce D George John Radcliffe Hospital Oxford. Control intestinal symptoms Optimise growth impaired at time of diagnosis in 88% Facilitate normal social development. Aims of Management of Crohn’s disease in adolescence. Emergency perforation
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Peri-anal disease and IBD in Adolescence Bruce D George John Radcliffe Hospital Oxford
Control intestinal symptoms Optimise growth impaired at time of diagnosis in 88% Facilitate normal social development Aims of Management of Crohn’s disease in adolescence
Emergency perforation bleeding acute colitis Elective obstruction fistula chronic ill health/failure of medical therapy Indications for Surgery in Crohn’s disease
Also delayed growth In adolescence
Similar to adults: operate as soon as there is an indication play safe minimal resection But also: earlier surgery to facilitate growth and to avoid steroids Principles of surgery in adolescence
Aggressive disease Early recurrence Psychological chronic ill health body image height, weight sexual development stoma Difficult problems
Acute colitis Failure of medical therapy chronic disease recurrent acute attacks Dysplasia Impaired growth Indications for surgery in Ulcerative Colitis
Overall fitness steroids, co-morbidity Colon certainty of diagnosis Psychology acceptability of stoma Sphincters manometry, U/S Nerves and tubes pelvic dissection Factors to consider
Proctocolectomy and end ileostomy Proctocolectomy and ileal pouch reconstruction Colectomy and ileostomy (rectal stump) Colectomy and ileorectal anastomosis Surgical options in ulcerative colitis
Consider colectomy and ileorectal in teens Completion proctectomy and pouch later UC in Adolescence
Anal Crohn’s disease 20-80% of patients with Crohn’s get perianal disease Rectal > colonic > ileocaecal > small bowel Anal Crohn’s disease
Primary Fissures Skin tags Ulcers Secondary Abscess/fistula Strictures Vaginal fistula (malignancy) Clinical features
Benign fissures, tags Variable fistulae, strictures Aggressive cavitating ulcers, sepsis Variable natural history
General Large bowel colonoscopy Small bowel small bowel enema Anus inspection EUA ultrasound, MRI Assessment of Anal Crohn’s disease
Minimise symptoms Prevent complication sepsis incontinence unhealed wounds stenosis Aims of Treatment of Anal Crohn’s
Do nothing Diet elemental, TPN Medical antibiotics, immunosuppressants, anti-TNF alpha Surgery drain sepsis, local procedures, distant resection, defunction, proctocolectomy Treatment Options
Skin tags leave alone Haemorrhoids surgery contraindicated Fissures if painless leave alone if painful GTN, Botulinum Treatment of Specific Lesions
Low Fistula may heal spontaneously if no rectal inflammation lay open
High fistula unlikely to heal ensure sepsis drained anti-TNF alpha ?fibrin glue defunction proctocolectomy
Anal Ulcers poor prognosis maximal medical therapy defunction proctocolectomy
Thorough assessment Tailoring treatment to individual Symptom control Prevention of complications Accept defeat Summary of Anal Crohn’s Disease