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Research Opportunities to Address Interactions Between Neglected Tropical Diseases & HIV

XIX International AIDS Conference. Research Opportunities to Address Interactions Between Neglected Tropical Diseases & HIV. 25 July 2012. Lee Hall, MD, PhD. Chief, Parasitology & International Programs Branch Division of Microbiology & Infectious Diseases.

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Research Opportunities to Address Interactions Between Neglected Tropical Diseases & HIV

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  1. XIX International AIDS Conference Research Opportunities to Address Interactions Between Neglected Tropical Diseases & HIV 25 July 2012 Lee Hall, MD, PhD Chief, Parasitology & International Programs Branch Division of Microbiology & Infectious Diseases

  2. Interactions Between NTDs & HIV Are Bidirectional HIV Neglected Tropical Diseases

  3. Some Potential Effects of NTD-HIV Coinfections • Changes in Disease Progression or Clinical Manifestations • Changes in Transmissibility • Changes in Susceptibility • Impacts on Diagnostic Sensitivity or Specificity

  4. Some Potential Effects of NTD-HIV Coinfections: Research Considerations • Qualitative vs. Quantitative Changes? • What Mechanisms Are Responsible for the Changes? • Are the Changes Reversible? Preventable? • What Would Be Considered a Meaningful Effect? • Do We Have Adequate Tools to Reverse or Prevent Changes? • What Alternatives Are Available to Achieve the Desired Changes?

  5. Research Opportunities: Funding Mechanisms • Investigator-Initiated • Research Projects • R01 Research Project Grant • R03 Small Grant • R21 Exploratory/Developmental Grant • Clinical Trials • R34 Clinical Trial Planning Grant • U01 Clinical Trial Implementation Grant • mR01 Milestone-driven Clinical Trial Implementation Grant • Solicited Research Activities • See NIAID Home Page (www.niaid.nih.gov) for Funding Opportunity Announcements • Research Resources

  6. Research Opportunities: Examples of Research Resources • Filariasis Research Reagent Resource Center (FR3) • SchistosomiasisResource Center • International Collaborative Network for the Study of Human HelminthCo-infections • HIV/AIDS Clinical Trials Networks

  7. For More Information: www.niaid.nih.gov • NIAID Home Page

  8. Thank you!

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