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A Guide On Using Meres100

A Guide On Using Meres100<br>

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A Guide On Using Meres100

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  1. Sirolimus Eluting BioResorbable Vascular Scaffold System Next Genera?on BioResorbable Scaffold. Low profile, 1.2 mm & deliverable system Optimal side branch access 100 µm Hybrid cell design gth, 2 en tr s l a i d a rh g i H 2 .3 0 Scaffold backbone PLLA 100 µm strut thickness¹ N o i t a ry r e t r a o t d l o f f a c s % 4 2 Closed cell Open cell 1 recoil, w o L .2 3% Low balloon overhang, short, abrupt balloon shoulders Drug coat of PDLLA + Sirolimus 1.25 µg/mm² Degradation over 3 years Couplets of tri-axial RO markers at either end² High vessel conformability² Size Matrix Diameters - 2.50, 2.75, 3.00, 3.25, 3.50, 4.00, 4.50 mm Lengths- 13, 16, 19, 24, 29, 32, 37, 40 mm

  2. N = 108, Prospec?ve, Non-Randomized, Mul?-Centre Study (16 Inves?ga?ng sites in India) Primary Demographics-Treatment Influencing Factors Diabe?cs (28%), Hypertensive (42%), Dyslipidemics (13%), Smokers (17%) Lesion characteris?cs- Lesion class A (7%), B1 (32%), B2 (56%), C (5%) Post Dilata?on 108 (100%)and Device Success 108 (100%) Clinical Endpoint at 1-Year* 6-Months f/up* 1-Year In-Hospital N = 108 (100%) 1-Month N = 108 (100%) 6-Months N = 108 (100%) ) N= 107 (99%) 0.2 1.0 0.75 Percentage (%) 0.15 ± 0.23 Binary Restenosis 0% 0.15 0.50 0.14 ± 0.22 Late Lumen Loss (mm) 0.25 0.0 0.10 –0.2 0.0 0.50 1.0 1.50 In-scaffold Late Lumen Loss at 6 months (mm) 0.07 ± 0.29 0.06 ± 0.15 0.05 0 In-Scaffold In-Segment Proximal Edge Distal Edge CTA 1-Year f/up 2 MLA: 7.41 mm Baseline 6-Months f/up 2 MLA: 7.36 mm OCT at 6-Months showed virtually complete strut coverage (99.3%) CTA at 1-Year showed low mean area stenosis of 11.33%

  3. 53 Years | Male | Diabe?c | Hypertensive | No family history | Non-smoker | Stable angina Diagnos?c Angio Final Result MeRes100 3.50 x 19 mm Baseline OCT 6-Months f/up 6-Months OCT f/up

  4. SCAFFOLD BACKBONE Scaffold Material Scaffold Strut Thickness Scaffold Diameters Scaffold Lengths : BioResorbable PLLA (Poly L-lactide) : 100 µm : 2.50, 2.75, 3.00, 3.25, 3.50, 4.00, 4.50 mm : 13, 16, 19, 24, 29, 32, 37, 40 mm SCAFFOLD RO MARKERS Tri-axial RO Markers TOP COAT-DRUG+POLYMER Drug Equivalent Drug Dose Polymer : Platinum (Couplets of tri-axial RO markers at either end, 120° apart from each other) : Sirolimus : 1.25 µg / mm : BioResorbable PDLLA (Poly D, L-lactide) 2 DELIVERY SYSTEM Delivery System Nominal Pressure (NP) Rated Burst Pressure (RBP) Balloon Overhang Shaft Outer Diameter Radiopaque Markers Usable Catheter Length Guide Catheter Compatibility Max. Guidewire : Rapid Exchange : 9 atm : 16 atm : < 0.5 mm : Proximal 1.95 F / Distal 2.7 F : 2 - Platinum / Iridium : 140 cm : 6 F (Min. I D 0.070" / 1.8 mm) : 0.014'’ (0.36 mm)

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