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Natural products and ecological interactions Adaptive evolution (i.e. “rapid”). Scents. Colours. Flavours. Pests. Pathogens. Allelopathy. The gene cluster is close to the telomere. 15 kb Sad1 probe. Where synteny breaks down…. Rapidly evolving regions of genomes
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Natural products and ecological interactionsAdaptive evolution (i.e. “rapid”) Scents Colours Flavours Pests Pathogens Allelopathy
The gene cluster is close to the telomere 15 kb Sad1 probe
Where synteny breaks down… • Rapidly evolving regions of genomes • Conserved motifs shared by co-regulated genes • Determining the sequence of evolution of members of multigene families • Determining the sequence of evolution of combinations of genes
Wish list • Reliable ORF designations; reliable sequence information • Sceptical of text annotation – prefer using a set of “probe” sequences or Pfam domains • Positional information – Genomic context • Searchable gene expression data (Genevestigator-like) • Recombination frequencies • Degree of divergence across accessions/species/broader