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B*35:01 B*35:05 Supplementary Figure 2. Flexibility difference at residue 97 between HLA-B*35:01 and HLA-B*35:05. Residue 97 in HLA-B*35:01 (Arg (R)) and HLA-B*35:05 (Ser (S)) shown in color, and their surrounding amino acids (<8Å) are represented by white space filling spheres. View from above (A and B), B pocket side (C and D), and F pocket side (E and F) are shown. A B B*35:01 B*35:05 C D B*35:01 B*35:05 E F