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This study investigated callosal morphological alterations in schizophrenia using magnetic resonance imaging (MRI). Schizophrenic patients (n = 25) and normal controls (n = 28) were compared. Parametric surface modeling accurately represented callosal surfaces. Results revealed the vertical movement of the corpus callosum, thicker superior and inferior surfaces, and larger anterior and posterior regions in male patients. Special thanks were given to Dr. Tonmoy Sharma and his team for providing all the data. This study couldnu2019t have continued without it.
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Mapping Morphology of the Corpus Callosum in Schizophrenia This study investigated callosal morphological alterations in schizophrenia using magnetic resonance imaging (MRI). Schizophrenic patients (n = 25) and normal controls (n = 28) were compared. Parametric surface modeling accurately represented callosal surfaces. Results revealed the vertical movement of the corpus callosum, thicker superior and inferior surfaces, and larger anterior and posterior regions in male patients. Special thanks were given to Dr. Tonmoy Sharma and his team for providing all the data. This study couldn’t have continued without it. Further research is needed to understand the underlying mechanisms, diagnostic and treatment implications, and potential therapeutic strategies related to structural abnormalities in the corpus callosum of male schizophrenic patients found in this study using MRI. Article Link: https://academic.oup.com/cercor/article/10/1/40/377106