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February 27, 2019. A Cognitive self-management intervention for persons with multiple sclerosis. Janet Morrison, PhD, RN, MSCN Research Associate V.
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February 27, 2019 A Cognitive self-management intervention for persons with multiple sclerosis Janet Morrison, PhD, RN, MSCN Research Associate V Research reported here was supported by the National Institute of Nursing Research of the National Institutes of Health under Award Number P30NR015335. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Background • Chronic immune-mediated degenerative disease of the CNS • Prevalence ~ 900,000 in US • 3:1 Female to male ratio • Variable and unpredictable symptoms • Fatigue • Depression • Sleep disturbance • Mobility • Impaired cognitive function • Significant impact on maintaining employment, self-management, QoL
Study Design • Pilot RCT • Intervention (n=8) • 8 weekly 90-minute virtual group sessions • Self-Management • Chronic Disease and Cognitive Function • Remote, web-based video conferencing • Enhanced usual care (n=8)
Outcomes Self-Report • MS self-management • Self-efficacy • Managing medications, symptoms and daily activities • Cognitive function • Depression • Fatigue • Sleep disturbance Performance Neuropsych • Language • Executive function • Attention • Working and episodic memory • Processing speed Physiologic • Physical activity • Sleep
Proof of Concept • Web-based video conferencing • Attendance (mean = 7 + .92) • Positive participant feedback
Strengths & Limitations • Small sample size (N=16) • Variability • Lack of power • Intensity of intervention
Next Steps • Comparative effectiveness trial • More sensitive outcome measures • Repeated measures design