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Neurologic Disorders. Jan Bazner-Chandler CPNP, CNS, MSN, RN. The Brain . Differences in Children. Biological Differences. Fibrous union of suture lines and interlocking of edges occurs by 6 months solid union requires approximately 12 years. Biological Differences.
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Neurologic Disorders Jan Bazner-Chandler CPNP, CNS, MSN, RN
Biological Differences • Fibrous union of suture lines and interlocking of edges occurs by 6 months solid union requires approximately 12 years.
Biological Differences • At birth, brain is 25% of adult size • By age 5, brain is 90% of adult size • CSF is 5 ml in a neonate and 150 ml in adult • Myelinization is complete by puberty • Spinal cord terminates at L3 in infant
Developmental Differences • Handedness before age 1-year may be associated with focal lesion. • Reflexes present at birth disappear by 1 year. • Neurological assessment of the child is limited to their developmental level.
Neurologic Exam • Level of consciousness • What stimuli is needed? • What is quality of the response? • What is length of response? • Most important indicator of neurologic function
Levels of Consciousness • Confusion • Disorientation to time, place, or person • Delirium • Characterized by confusion, fear, agitation, hyperactivity, or anxiety • Stupor = response to vigorous stimuli only • Coma = severely diminished response
Glasgow Coma Scale • Designed as a standardized assessment of the patient with disturbed consciousness. • The lower the score at time of admission the poorer the outcomes.
Pupil Changes Fixed and dilated pupil(s) is neuro emergency Whaley & Wong
Pupil Changes • Pin point pupils suggest narcotic overdose. • Midpoint fixed pupils suggest structural damage in the midbrain. • Dilated or large pupils indicate severe anoxia or overdose. • One pupil fixed and dilated suggests herniation of the the temporal lobe.
Decoritate posturing Decerebrate posturing Whaley & Wong
CT Scan Non-invasive three dimensional look at normal and abnormal structures.
MRI Image body tissue or organs in action.
Brain Tumor CT Scan MRI
Brain Scan Injection of tiny amounts of radioactive isotope to measure tissue uptake.
Lumbar Puncture Side lying position for LP
Lumbar Puncture Insertion of spinal needle into subarachnoid space between the lower lumbar vertebrae. Waley & Wong Modified sitting position for LP
Normal CSF Clear odorless WBC’s 0 – 5 Protein 15 to 45 Glucose 50 – 80 Pressure 50 to 180 Abnormal CSF Turbid, cloudy WBC’s 1000 – 2000 Protein 100 – 500 Glucose lower than blood sugar Pressure 180 or greater Cerebral Spinal Fluid
Intracranial Pressure • The head is a closed box • Total volume inside brain V brain + V blood + V CSF + V other = Constant
Volume of Brain • Brain volume can increase with: • Edema • Blood flow • Bleed within the brain • Tumor
Volume - Other Medlib.utah.edu Ventricular bleed in a 28 week neonate
Vital Sign Changes Increase in Blood Pressure Cushing Triad Altered Respiratory pattern Decrease in Pulse
Vital Signs • Pulse rate decreases as ICP increases • Respirations: rate, quality, and characteristic change • Initially slow as ICP rises rate becomes rapid and noisy leading to apnea • Blood pressure rises slowly / late sign is widening pulse pressure
Nursing Assessment • Glasgow coma scale • Pupil size • LOC • Vital signs • Accurate I & O • Minimize metabolic demands • Fever, pain, seizures
Medical Management • Controlled hyperventilation • Evacuation of hematoma • Correction of CSF increase • Steroids / dexamethasone • Correction of coagulopathies
Keep Kids Safe Children.com
Alterations in Neurologic Status • Seizures: a paroxysmal , uncontrolled episode of behavior that results from an abnormal electrical discharge from the brain.
Effect on Child • Altered responsiveness • Altered sensation or perception • Altered movements, mobility or muscle tone
Classification of Seizures • Partial • No loss of consciousness • Symptoms depend on what area of the brain is involved • Often presents as a staring episode or slight twitching of eyes and drooling • Generalized • Tonic-clonic • Sudden loss of muscle tone • Eye blinking, alter awareness, mouth, or facial movement
Status Epilepticus • Seizures lasting more than 30 seconds • Serial seizures without return to baseline • Medical emergency
Febrile Seizures • Occurs in 2 to 5% of all children • 6 months to 6-years of age • The younger the child the more likely they are to re-occur • Familial tendency • Treatment: phenobarbital or diazepam (only if second febrile seizure)
Documentation • When seizures began • Duration • Warning signs • Clinical characteristics • Level of consciousness • Signs and symptoms when seizures stops
Interventions • Remain calm and stay with child • Protect child from injury • Provide time for child to recover • Reassure and provide support to child and others • Document
Diagnostic Tests • Febrile seizure: Lumbar puncture • Seizures • EEG • Electrolytes • MRI • Medications • Dilantin causes overgrowth of gum tissue
Ancephaly Absence of brain tissue above a rudimentary brain stem and basal ganglia. med.utah.edu
Ancephaly Diagnostic Tests • Prenatal ultra-sound • Elevated alpha fetal protein • Multiple anomalies • Incompatible with life • Heart transplant donors
Interventions • Supportive care • Genetic and psychological counseling • Organ donation • Grief therapy • Sustained extra uterine life impossible
Spina Bifida Cystica • Incomplete fusion of one or more vertebral laminae, resulting in an external protrusion of the spinal tissue. • 5 per 10,000 births • Other anomalies
Contributing factors • Poor maternal nutrition • Maternal age • Pregnancy history • Birth order • Socioeconomic status
Diagnosis Ultrasound Elevated AFP 95% survival rate med.utah.edu
Spina Bifida Bowden & Greenberg
Myelomeningocele • A protruding saclike structure containing meninges, spinal fluid and neural tissue.
Assessment at Birth • Size, level, nature of tissue covering • Nerve involvement • Lower limbs / bowel and bladder function • Degree of hydrocephalus • Head circumference • Leakage of CSF • Cranial sutures
Interventions • Protect from injury and infection • Rupture of the sac can lead to death • Sterile moist dressing on sac until surgery • Position to prevent pressure on back
Goals of Surgery • Control infection • Provide a normal anatomic barrier • Provide a normal anatomic barrier • Control hydrocephaly
Outcomes • Bladder and bowel problems • Latex allergies: due to in and out catheterization • Problems with self-esteem • Orthopedic management • Schooling based on IQ
Hydrocephalus • Greek meaning water on the brain • Dilation of the ventricles • Two primary causes: • Congenital .5 to 1% • Acquired: • Lesion, tumors, infection, intracranial bleed, myelomeningocele